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1、胃恶性纤维组织细胞瘤临床病理特征白辰光柯儒斌杨蕾马大烈白辰光，杨蕾，马大烈，第二军医大学长海医院病理科上海市200433柯儒斌，余杭区人民医院病理科浙江省杭州市国家自然科学基金资助项目,No.30471702.通讯作者：马大烈,200433,上海市杨浦区长海路174号，第二军医大学长海医院病理科.madalie@126.com,电话：021-25074853收稿H期：2006-接受H期：Primarymalignantfibroushistiocytomaofthestomach:twocase
2、reportsandreviewoftheliteraturesChen-guangBai,Ru-binKe,LeiYang,Da-lieMaCheguangBai,LeiYang,Da-lieMa,Departmentofpathology,Chang-haihospital,Shanghai200433,ChinaRu-binKe,Departmentofpathology,Yuhangpeople'shospital,Hangzhou200000,ZhejiangProvince,Chin
3、aSupportedbyNationalNaturalScienceFoundationofChina,No.30471702Correspondenceto:Da-lieMa,Departmentofpathology,Chang-haihospital,Shanghai200433,China.madalie@126.comReceived:2006-Accepted:AbstractAIM:Tostudyclinicalandpathologicalfeaturesofmalignantf
4、ibroushistiocytomainthestomach.METHODS:Todescribetwopatientswithprimarymalignantfibroushistiocytomaofthestomach,andtoreviewliteratureinEnglishandChinese>RESULTS:Thefirstcasewasa71-year-oldmanwithepigastralgiaanddarkstools.Thesecondcasewasa34-year-oId
5、manwithepigastralgiaandvomiting.Bothtumourswerebig,whiteandlocatedinthesubmucosallayerofposteriorwallofthegastriccorpus・Histologically^itwascomposedofamixtureofpleomorphicfibroblast-likespindlecells,focallyarrangedinasteriformpattern,ovaltoroundhisti
6、ocyte-likecellsandinflammationcells.Immunohistochemically,thetumorcellsexpressedvimentin,CD68,Lysozymeandalpha-1-antitrypsin,butwerenegativeforothermarkers.CONCLUSION:Malignantfibroushistiocytoma(MFH)inthestomachisveryrare.Keywords:Neoplasmofthestoma
7、ch;Malignantfibroushistiocytoma;ClinicalandpathologicalfeaturesChen-guangBai,Ru-binKe,LeiYang,Da-lieMa.Primarymalignantfibroushistiocytomaofthestomach:twocasereportsandreviewoftheliteratures.ShijieHuarenXiaohuaZazhi2006摘要目的:探讨原发于胃的恶性纤维组织细胞瘤的临床病理学特征。方
8、法:报道2个胃恶性纤维组织细胞瘤病例，并复习国内外文献。结果：2例均为男性，年龄34及71岁。肿物体积大，均位于胃体后壁。切面灰白色，编织状，质韧，肿物位于粘膜下，累及胃壁全层，粘膜面形成溃疡。镜下示：梭形纤维母细胞样肿瘤细胞呈交织状及束状排列，胞浆红染，核卵圆形，人而界型，并见较多单核及多核瘤巨细胞，其间见组织细胞样瘤细胞散在分布，可见数量不等的炎细胞散在分布。免疫表型:Vimentin弥漫阳性，Al-ACT、CD68及Lysozyme部分细胞阳性。结论：胃恶性纤维组织细胞瘤是一种罕见的肿瘤，
