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1、热淋清片联合诺氟沙星片治疗单纯性尿路感染的临床观察武警重庆总队医院药剂科周燕萍白海燕(重庆400061)摘要口的:观察热淋清片联合诺氟沙星片口服治疗单纯性尿路感染的疗效。方法:116例单纯性尿路感染患者随机分为治疗组和对照组(每组各58例),治疗组33例,给予热淋清片5片,口服,每天3次,诺氟沙星片0.3g,口服,每天2次;对照组仅给予诺氟沙星片0.3g,口服,每天2次,7天1疗程,所冇患者均随访28天,记录临床症状、体征、血常规、尿常规、尿培养和药物副作用。结果:治疗组和对照组的治愈率和总有效率分别为82.8%,93.1%和60.3%,7
2、2.4%,两组相比有显著性差异(PV0.05)。治疗组的乐路刺激症状、肾区痛、血尿和发热的消失时间明显短于对照组,治疗组的细菌清除率明显高于对照组。结论:热淋清片联合诺氟沙星片II服是治疗单纯性尿路感染的有效方案,值得临床推广应用。关键词尿路感染;热淋清片;诺氟沙星片;疗效ClinicalObservationontheTreatmentoftheSimpleInfectionofUrinaryTractwithRelinqingTabletandNorfloxacinTabletZhouYan-pingBaiHai-yanDepartme
3、ntofPharmacy,theGeneralHospitalofChongqingAnnedPolice・Chongqing,China,400061【Abstract]ObjectivetoevaluateclinicaltherapeuticeffectivenessofrelinqingtabletcombinedwithNorfloxacintabletonthesimpleinfectionofurinarytract.Methods116casesofpatientswithsimpleinfectionofurinarytr
4、actwererandomlydividedintothetreatinggroupandcontrolgroup・thetreatinggroupwerereceivedrelinqingtablet5,oraladministration,takenwithwarmwater,3timesaday;andoralNorfloxacin0.3g,2timesaday;thecontrolgrouponlyoralNorfloxacin0.3g,2timesaday,theperiodoftreatmentwas7days,allthepa
5、tientswerefollowedupfor28days,theclinicalsymptoms,signsandtheresultsofbloodroutineexamination,urineroutineexaminationandurinecultureandthesideeffectwererecorded・Resultsthecurerateandthetotaleffectiverateoftreatinggroupandcontrolgroupwere82.8%,93.1%and60.3%,72.4%respectivel
6、y,thedisappearedtimeofirritabilityofurinarytract,renalpain,hematuriaandfeverintreatinggroupwasobviouslyshorterthanthoseincontrolgroup,theeliminaterateofbacteriaintreatinggroupwashigherthanthatincontrolgroup・ConclusionrelinqingtabletcombinedwithNorfloxacintabletoraldelivery
7、canbeusedasaneffectivedrugschemeonthesimpleinfectionofurinarytractandisworthyofpopularizationandapplicationonclinic.【keywords]infectionofurinarytract;relinqingtablet;Norfloxacintablet;efficacy尿路感?ft(UrinaryTractInfection,UTI)是指细菌(极少数可由真菌、原虫、病毒)等病原微生物在尿路屮生长繁殖,侵犯尿道粘膜或组织而引起的炎
8、症,是仅次于呼吸道及消化道的感染性疾病。单纯性尿路感染是指发牛于泌尿系统的解剖结构功能正常而乂无糖尿病或免疫功能低下等合并症患者的尿路感染⑴。虽然使用抗菌药物能够有效治疗单纯性乐