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1、消化道前肠神经内分泌肿瘤的临床特点分析DOC格式论文,方便您的复制修改删减消化道前肠神经内分泌肿瘤的临床特点分析(作者:单位:邮编:)【摘要】目的分析消化道前肠神经内分泌肿瘤(NET)的临床和病理特点,以提高对该类疾病的认识与诊治水平。方法对40例消化道前肠NET病人的资料进行回顾性分析,总结其临床特点。结果40例NET病人中,胃NET25例(62.5%),十二指肠NET11例(27.5%),壶腹NET4例(10.0%)。胃、十二指肠和壶腹NET的男女比例分别为1:1.5、1.2:1和3:1090.9%的十二指肠NET位于球部和降部。胃和十二指肠NET临床表现以腹痛为最多见,分别
2、为40.4%和45.5%;病理类型以I型为主,分别为68.0%和63.6%,肿瘤直径2cm时很少发生转移。壶腹NET主要表现为黄疸(75.0%),以II型为主,占75.0%,直径2cm即可发生转移。胃、十二指肠和壶腹NET发生转移率分别为16.0%、27.3%>75.0%。结论消化道前肠NET以胃NET为最多见。胃NET以女性为主,而十二指肠和壶腹NET男性多见。十二指肠NET好发于球部和降部。胃和十二指肠NET以上腹痛为最多见,组织学类型以I型为主。壶腹NET主DOC格式论文,方便您的复制修改删减要临床表现为黄疸,以II型为主。胃和十二指肠NET直径2cm较少转移,而壶腹NET
3、有转移的倾向,其肿瘤大小与转移潜能无关。[ABSTRACT]ObjectiveToanalyzetheclinicalandpathologicalcharacteristicsofgastrointestinalforegutneuroendocrinetumors(NETs)andraisethelevelofunderstandinganddiagnosisoftheconditionsofthiscategory.MethodsAretrospectiveanalysisof40caseswithforegutNETswasdone,andtheirclinicalcha
4、racteristicssummarized・ResultsOfthe40casesreviewed,theNETofstomach,25cases(62.5%);thatofduodenum,11(27.5%);ofampullaofvater(AV),four(10.0%).Malefemaleratioinstomach,duodenumandAVwas1:1.5,1.2:1,and3:1,respectively.ForduodenalNET;90.9%locatedatthefirstandsecondpartoftheduodenum.Abdominalpainwas
5、themostcommonsymptomingastricandduodenalNETs,accountingfor40.4%and45.5%,respectively;themainhistologicaltypewastypeI,being68.0%and63.6%,respectively;metastasiswasrarewhenthetumorwas2cm.ThemainsymptomoftheAVwasjaundice(75.0%);mainlytypeIIinhistology(75.0%),metastasismightoccurwhenthetumor2cm.T
6、hemetastasisratesofNETinstomach,duodenumandAVwerel6.0%,27.3%and75.0%,DOC格式论文,方便您的复制修改删减respectively.ConclusionInalimentarytractNETs,gastricNETisthemostcommonlyseen,mostlyinfemale;andthatofduodenum,locatedmainlyatbulbarzoneanddescendingpart,andAV,mostlyinmale.Abdominalpainwasthemostcommonsympt
7、om,withhistologyoftypeI.JaundiceisthemainmanifestationofNETinAV,withhistologyoftypeII・LessmetastasiswasseeningastricandduodenalNETswhenthesizeoftumorwas2cm;thereismetastatictendencyofNETinAV,itsmetastaticpotencyisnotassociatedwiththesizeoftum