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1、苏州地区心肺复苏术后早期目标治疗状况【摘要】目的评估苏州地区心肺复苏术后患者早期目标化治疗的状况，为今后完善复苏后规范化治疗提供临床资料。方法采用回顾性队列研究的方法，调查2009-2010年期间苏州地区10家二级甲等及以上综合性医院，其ICU内收治的院内或院外心脏骤停恢复自主循环患者的资料。采集心脏骤停后48h内主要目标化治疗指标：体温(T)、平均动脉血压(MAP)、末梢血氧饱和度(SpO2)、二氧化碳分压(PaCO2)和末梢血糖(Glu)的测定值，比较分析上述指标达到目标值的情况。结果共有101例心脏骤停患者进入本研究。在目标化治疗指标达
2、标率中，Sp02和MAP的达标率分别为90.1%和81.4%；Glu和PaCO2的达标率分别为55.4%和32.8%；而治疗性亚低温(MTH)的达标率最低，仅为10%；上述日标化治疗指标达标率之间的差异具冇统计学意义(P<0.01)o结论苏州地区心肺复苏术后患者的目标治疗质量仍需提高，尤其应强化对PaC02和体温的管理力度。【关键词】心脏骤停；心肺复苏；早期目标治疗；治疗性亚低温；平均动脉血压；末梢血氧饱和度；二氧化碳分压；末梢血糖Asurveyontheimplementationoftheearlygoal-directedtherapy
3、aftercardio~pu1monaryresuscitationinSuzhouareaZHUJian-liang,ZHANGYan,YANGLin,LIULi-jun.DepartmentofEmergencyandCriticalCareMedicine,TheSecondAffiliatedHospitalofSoochowUniversity,Suzhou,215004,ChinaCorrespondingAuthor:LIULi~jun,Email:lijunliusz@hotmail,com[Abstract】0bjectiv
4、eToevaluatetheimplementationoftheearlygoal-directedtherapyaftercardio-pulmonaryresuscitationinSuzhouarea,inordertoprovideclinicaldataforstandardizedpostresuscitationcare.MethodsThisretrospectivestudyineludedcomatosesurvivorsofCA,admittedintointensivecareunits(ICU)of10hospit
5、alsinSuzhouareabetwoonJanuary2009andDecember2010.theparameters,meanarterialpressure(MAP),peripheraloxygensaturation(Sp02),partialpressureofcarbondioxide(PaC02),bloodglucose(Glu)andbodytemperature(T),werecollectedfor48hafterCA.Thepercentageofparametersachievingrecommendedgoa
6、lswascompared・ResultsAtotalof101CApatientswereenrolledinthisstudy.AmongtheparametersofGDT,thepercentageofachievingrecommendedgoalsforSp02andMAPwas90.1%and81.4%；thepercentageofachievingrecommendedgoalsforGluandPaC02was55.4%and32.8%；however,mildtherapeutichypothermia(MTH)reac
7、hedthelowestpercentage,only10%；thereweresignificantdifferencesinthepercentageofachievingrecommendedgoalsfortheseparameters,P<0.01.ConclusionsThequalityofearlygoal-directedtherapyintheCApatientsshouldbeimproved,especiallyinthemanagementofbodytemperatureandpartialpressureofca
8、rbondioxide.[Keywords]Cardiacarrest；Cardio-pulmonaryresuscitation；Ear1ygoal-direct
