补肾活血汤治疗帕金森病的临床研究

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1、补肾活血汤治疗帕金森病的临床研究［摘要］目的观察补肾活血汤治疗帕金森病的临床效果。方法将山西省太原市迎泽区郝庄镇中心•卫生院2011年1月〜2013年12月收治的64例帕金森病患者随机分为治疗组与対照组，每组各32例。对照组患者给予多巴丝腓片治疗，治疗组在对照组的基础上加用补肾活血汤治疗。两组均以4周为1个疗程,连服3个疗程o采用统一帕金森病评定量表(UPDRS)进行评分，评价疗效并观察不良反应。结果与治疗前比较，两组UPDRS量表各项评分及总分均明显降低，差异有统计学意义(PV0.05)；两组治疗后UPDRS量表各项评分及总分比较差异有统计学

2、意义(PV0.05)。治疗组总冇效率(87.50%)明显高于对照组(65.63%),差异冇统计学意义(P<0.05)o两组不良反应发生率比较(12.50%vs18.75%),差异无统计学意义(P>0・05)。结论补肾活血汤治疗帕金森病，能明显改善睡眠障碍、情绪和精神状态，提高患者的口常生活能力，提高运动功能，从而从整体上改善患者的生活质量，值得临床推广。［关键词］帕金森病；补肾活血汤；多巴丝腓片［中图分类号］R742：文献标识码］A［文章编号］1674-4721(2014)05(b)-0113-03ClinicalstudyofBushenHu

3、oxuedecoctioninthetreatmentofParkinsondiseaseNIUXiao-yingHaozhuangTownHealthCenterofYingzeDistrictinTaiyuanCity,Taiyuan030045,China[Abstract]ObjectiveToobservetheclinicaleffectofBushenIluoxuedecoctioninthetreatmentofParkinsondisease.Methods64caseswithParkinsondiseaseadmitted

4、toHaozhuangCountyHealthCcntorofYingzoDistrictinTaiyuanCityfromJanuary2011toDecember2013wererandomlydividedintotreatmentgroupandcontrolgroup,with32casesineachgroup・Thecontrolgroupwastreatedwithlevodopaandbenserazidetablet.TreatmentgroupwasaddedwithBushenHuoxuedecoctiononbasis

5、ofcontrolgroup.Bothgroupsweretaken4weeksasacourse,continuousfor3courses・UPDRSwasusedtograde,andtoevaluatetheefficacy.Thesideeffectswereobserved.ResultsComparedwithbeforetreatment,everyscoresandtotalscoresofUPDRSinthetwogroupswerealldecreased,thedifferenceswerestatisticallysi

6、gnificant(P<0.05).ThedifferencesofeveryscoresandtotalscoresofUPDRSaftertreatmentinthetwogroupswerestatisticallysignificant(P<0.05).Thetotaleffectiverateoftreatmentgroup(87.50%)wassignificantlyhigherthanthatofcontrolgroup(65.63%)(P<0.05).Thedifferenceoftheincideneeofsideeffec

7、tsbetweenthetwogroups(12.50%vs18.75%)wasnotstatisticallysignificant(P>0.05).ConclusionBushenIluoxuedecoctioninthetreatmentofParkinsondiseasecansignificantlyimprovesleepdisorders,emotionalandmentalstate,enhanceactivityofdailyliving,improvemotor*function,soastoimprovequalityof

8、lifeasawhole,whichisworthyofclinicalpromotion.［Keywords］Parkinsondisease;Bu