补肾活血方治疗帕金森病的临床研究

《补肾活血方治疗帕金森病的临床研究》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、补肾活血方治疗帕金森病的临床研究补肾活血方治疗帕金森病的临床研究［摘要］目的观察补肾活血方治疗帕金森病的临床效果。方法选择西安交通大学第二附属医院2006年9月〜2012年9月门诊及住院帕金森病患者70例，将其随机分为治疗组(35例)和对照组(35例)，治疗组给予补肾活血中药和西药美多巴，对照组单用美多巴，疗程均为3个月，采用英国帕金森病学会脑库帕金森病临床诊断量表(UPDRS)对两组患者治疗前后的症状进行评分；同时观察两组患者的非运动症状，包括失眠、便秘、多汗、精神障碍、乏力、不明原因导致的疼痛、认知障碍等的发生率。结

2、果治疗组用药前后的UPDRS评分差较对照组大，差异有统计学意义(P<0.05)；治疗后治疗组的非运动症状，如失眠、便秘、多汗、乏力的发生率与对照组比较，差异有统计学意义(P<0.05)；而精神障碍、不明原因导致的疼痛、认知障碍等虽较对照组有所降低，但差异无统计学意义(P>0.05)o结论补肾活血方可明显改善帕金森病患者的运动症状，同时对于非运动症状如失眠、便秘、多汗、乏力等亦有明显的改善。［关键词］帕金森病；美多巴；药物治疗；中西医结合［中图分类号］R742.5［文献标识码］A［文章编号］1673-7210(2014)0

3、8(a)-0099-04ClinicalstudyofParkinsondiseasetreatedwithBushenHuoxueDecoctionCHENSongshengMAQiaoyaWANGRuiliHUChuntingDepartmentofNeurology,CadreWard,theSecondAffiliatedHospitalofXi'anJiaotongUniversity,ShaanxiProvince,Xian710004,China［Abstract］ObjectiveToobservethe

4、clinicalefficacyofBushenHuoxueDecoctiononParkinsondisease・Methods70casesofParkinsondiseasewererandomlydividedintotreatmentgroup(35cases)andcontrolgroup(35cases)・Allthecasescamefromtheout-patientsandin-patientsoftheSecondAffiliatedHospitalofXianJiaotongUniversityf

5、romSeptember2006toSeptember2012.Intreatmentgroup,BushenHuoxueDecoctionandmadoparwereadministered・Incontrolgroup,madoparwasonlyadministered・Thedurationoftreatmentwas3months・TheunifiedParkinsondiseaseratingscale(UPDRS)wasusedtoscorethesymptomsandphysicalsignsbefore

6、andaftermedicationintwogroups・Theincidenceofnon-motorsymptomsoftwogroupswasobserved,includinginsomnia,profusesweating,mentaldisturbance,fatigue,unknownpain,cognitivedysfunction,etc・・ResultsBeforeandaftertreatment,UPDRSscoresweremuchmoredifferentintreatmentgroupwh

7、encomparedwithcontrolgroup,indicatingastatisticallysignificantdifference(P<0.05)・Aftermedication,intreatmentgroup,ofnon-motorsymptoms,theincidencesofinsomnia,defecationdysfunction,profusesweatingandfatigueweresignificantlydifferentinstatisticswhencomparedwithcont

8、rolgroup(P<0.05)；andthoseofmentaldisturbance,unknownpainandcognitivedysfunctiondecreasedascomparedwithcontrolgroup,buttherewasnosignificantdifference(P>0.05)・C