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1、联合化疗治疗乳腺癌临床治疗体会【摘要】目的对于联合化疗治疗乳腺癌的临床治疗体会进行探讨。方法本组75例，均为女性，年龄28~67岁，平均45❷3岁，术后均经病理证实。采用CAF方案29例，CMF方案25例，CEF方案12例，ET方案9例。所有患者化疗4〜6个疗程，每个疗程间隔28do结果本组病例就诊后24h内即明确诊断者70例（93❷33%）,就诊后2~4d内明确诊断5例（6❷67%）。本组75例中出现化疗药物外溢至皮下发生疼痛、红肿者5例，发生率6❷7%静脉炎19例，发生率25❷3%胃肠道反应71例
2、，发生率94❷7%,骨髓抑制23例，发生率30❷7%口腔炎26例，发生率34❷7%脱发57例，发生率76%。75例联合化疗治疗乳腺癌方案中，明显好转18例（24%）,轻度好转16例（21❷33%）,缓解不明显7例（9令33%）,无效34例（45❷33%）,有效率54❷67%。结论化疗药物虽可最大限度的杀死癌细胞，但其不良反应也不容忽视，化疗期间运用科学有效的护理方法，可以减轻化疗中出现的各种不良反应。【关键词】联合化疗乳腺癌临床治疗体会Combinationchemotherapytreatmentf
3、orbreastcancerZHOULin.WangchengCountyPeople^sHospital,SingaporeBranchofHopeTown,Wangcheng410205,China【Abstract】ObjectiveCombinationchemotherapyfortreatmentofbreastcancertreatmenttoexplore・Methodslnthisgroupof75patientswerefemale,aged28to67years,mean45❷3
4、years,wereconfirmedbypathologyafteroperation.29patientswithCAFprogram,CMFprogramin25cases,CEFprogramin12cases,ETprogramsin9cases・Allpatients4to6coursesofchemotherapy,eachtreatmentintervalof28d.ResultsAftertreatmentthegroupofcasesisdiagnosedwithin24h,70p
5、atients（93❷33%）,2~4daftertreatmentin5caseswerediagnosed（6❷67%）.75patientsinthisgroupappearedtosubcutaneouschemotherapyspilloccurs,painandrednessin5cases,theoccurrenceratewas6❷7%；phiebitisin19cases,incidence25❷3%；71casesofgastrointestinalreactions,theinc
6、idencewas94❷7%,23casesofbonemarrowsuppression,theoccurreneerateof30❷7%；stomatitisin26cases,incidence34❷7%；hairlossin57cases,theoccurreneerateof76%・75casesofchemotherapytreatmentforbreastcancerprograms,significantimprovementin18cases（24%）,mildimprovement
7、in16patients（21^33%）,reliefobviousin7cases（9❷33%）,ineffectivein34patients（45❷33%）,effective54❷67%.ConclusionAlthoughchemotherapydrugskillcancercellscanbemaximum,butitssideeffectscannotbeignored,chemotherapy,effectivecareduringtheapplicationofscientificm
8、ethods,chemotherapycanreducethevariousadversereactionsoccur.【Keywords]Combinationchemotherapy；Breastcancer；Clinicaltreatment；Experience乳腺癌是女性最常见的恶性乳腺癌之一，据资料统计，发病率占全身各种恶性乳腺癌的7%〜10%,在妇女仅次于子宫癌。它的发病常与遗传有关，以及40〜60岁之间，绝经期前后的妇女发病率较高。仅约1
