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1、联介化疗治疗乳腺癌的临床治疗体会【摘要】冃的对于联合化疗治疗乳腺癌的临床治疗体会进行探讨。方法本组75例,均为女性,年龄2旷67岁,平均453岁,术示均经病理证实。采用CAF方案29例,CMF方案25例,CEF方案12例,ET方案9例。所有患者化疗4飞个疗程,每个疗程间隔28d。结果本组病例就诊后24h内即明确诊断者70例(9333%),就诊后2〜4d内明确诊断5例(667%)。本组75例中出现化疗药物外溢至皮下发牛疼痛、红肿者5例,发生率67%静脉炎19例,发牛率253%胃肠道反应71例,发主率947%,骨髓抑制23例,发牛率307%口腔
2、炎26例,发生率347%脱发57例,发生率76%。75例联合化疗治疗乳腺癌方案屮,明显好转18例(24%),轻度好转16例(2133%),缓解不明显7例(933%),无效34例(4533%),有效率5467%。结论化疗药物虽町最大限度的杀死癌细胞,但其不良反应也不容忽视,化疗期间运用科学冇效的护理方法,可以减轻化疗中出现的各种不良反应。【关键词】联合化疗乳腺癌临床治疗体会CombinationchemotherapytreatmentforbreastcanccrZHOULin.WangchengCountyPeoplesHospital,
3、SingaporeBranchofHopeTown,Wangcheng410205,China【Abstract]Object!veCombinationchemotherapyfortreatmentofbreastcancertreatmenttoexplore.Methodslnthisgroupof75patientswerefemale,aged28to67years,mean453years,wereconfirmedbypathologyafteroperation.29patientswithCAFprogram,CMFpr
4、ogramin25cases,CEFprogramin12cases,ETprogramsin9cases・Al1pationts4to6coursesofchemotherapy,eachtreatmentintervalof28d.ResultsAftertreatmentthegroupofcasesisdiagnosedwithin24h,70patients(9333%),2〜4daftertreatmentin5caseswerediagnosed(667%)•75patientsinthisgroupappearedtosub
5、cutaneouschemotherapyspilloccurs,painandrednessin5cases,theoccurrenceratewas67%;phlebitisin19cases,incidenee253%;71casesofgastrointestinalreactions,theincidencewas947%,23casesofbonemarrowsuppression,theoccurrencerateof307%;stomatitisin26cases,incidenee347%;hairlossin57case
6、s,theoccurrencerateof76%.75casesofchemotherapytreatmentforbreastcancerprograms,significantimprovementin18cases(24%),mildimprovementin16pationts(2133%),reliefobviousin7cases(933%),ineffectivein34patients(4533%),effective5467%.ConclusionAlthoughchemotherapydrugskillcancercel
7、1scanbemaximum,butitssideeffectscannotbeignored,chemotherapy,effectivecareduringtheapplicationofscientificmethods,chemotherapycanreducethevariousadversereactionsoccur.【Keywords]Combinationchemotherapy;Breastcancer;C1inicaltreatment;Experience乳腺癌是女性最常见的恶性乳腺癌之<一,据资料统计,发病率占全身
8、各种恶性乳腺癌的7%^10%,在妇女仅次于子宫癌。它的发病常与遗传有关,以及40~60岁之间,绝经期前后的妇女发病率较高。仅约1%~2%的乳腺患者是男性。通常发生在乳房腺上皮组织