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1、2种牙菌斑控制法对胃黏膜幽门螺杆菌再感染的影响研究2种牙菌斑控制法对胃黏膜幽门螺杆菌再感染的影响研究作者:贾春玲姜广水杨学馨窦慧琴李翠荣作者单位:1.山东大学齐鲁医院口腔科;2•山东大学口腔医院综合科;3•山东大学齐鲁医院消化内科,山东济南250012【摘要】目的比较2种牙菌斑控制法对胃黏膜幽门螺杆菌(H.pylori)再感染率的影响,探讨H.pylori相关性胃病患者行菌斑控制的必要性及有效方法。方法将148例胃炎和消化性溃疡患者随机分为试验一组(54例)、试验二组(55例)和对照组(39例),
2、经消化内科抗H.pylori系统治疗并碳13尿素呼气试验证实H.pylori被根除后,试验一组行H常菌斑控制,试验二组除日常菌斑控制外增加牙菌斑的口腔专业处理,对照组未行上述处理。半年后行碳13尿素呼气试验检查确定各组胃黏膜H.pylori的感染率。结果试验一组屮5例患者因停用含漱液漱口被淘汰,试验二组屮8例患者因未严格执行牙菌斑控制被淘汰。试验一组、试验二组、对照组患者H.pylori的感染率分别为67.3%>19.1%、82.1%o统计分析表明,试验二组患者H.pylori的感染率低于对照组、
3、试验一组(?扌咅2=33,P<0.05;?描2=31.06,P<0.05),试验一组患者H.pylori的感染率与对照组之间无统计学差异(?扌咅2=2.43,0.1【关键词】菌斑控制胃黏膜幽门螺杆菌EffectsonHelicobacterpylorireinfectioningastricmucosabytwooralplaquecontrolmethodsJIAChun-lingl,JIANGGuang-shui2?YANGXue-xinl,DOUHui-qinl,LICui-rong3.(1
4、.Dept,ofStomatology,QiluHospitalofShandongUniversity,Jinan250012,China;2.Dept,ofGeneralDentistry,StomatologicalHospitalofShandongUniversity,Jinan250012,China;3.Dept,ofGastrointestinology,QiluHospitalofShandongUniversity,Jinan250012,China)[Abstract]Obj
5、ectiveToinvestigatethereinfectionrateofHelicobacterpylori(H.pylori)ingastricmucosabytwomeasuresoforalplaquecontrolonpatients,andtodemonstratethenecessityandbettermethodofplaquecon-trolonthosepatients・Methods148patientssufferedgastritisorgastroduodenal
6、ulcerwereassignedintotestgroup1(54patients),testgroup2(55patients)andcontrolgroup(39patients).13C-ureabreathtestprovedthattherewerenoH.pyloriintheirgastricmucosa.Dailyplaquecontrolwasusedintestgroup1,oralprofessorialinterventionswereaddedintotestgroup
7、2,neitherdailyplaquecontrolnororalprofessorialinterventionswasconductedincontrolgroup.Allpatientswereconducted13C・ureabreathtestagainafterhalfayeartodeterminethereinfectionrateofH.pyloriingastricmucosa.Results5patientswereeliminatedbecauseofstoppingmo
8、uthwashinthetestgroup1,8patientsfailedtocontroldentalplaqueinthetestgroup2.TheinfectionratesofH.pyloriingastricmucosaoftestgroup1,testgroup2andcontrolgroupwere67.3%,19.1%,82.1%,respectively.TheinfectionrateofH.pylorioftestgroup2waslowersignifi