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《左金丸加味辨证治疗反流性食管炎的临床疗效观察-中药新药与临床药理》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、左金丸加味辨证治疗反流性食管炎的临床研究李力强「2,张贵锋「2,曾艺文「2,王芳1，2,宾建平3,温鸿源2,谢君3(i.肇庆医学高等专科学校，广东肇庆526020；2.肇庆医学高等专科学校附属医院，广东肇庆526020；3.肇庆市中医院，广东肇庆526020)摘要：目的观察左金丸加味辨证治疗反流性食管炎的临床疗效。方法120例反流性食管炎患者随机分为观察组与对照组，每组60例；观察组采用左金丸加味辨证治疗，对照组采用奥美拉畔联合麦滋林治疗；3个疗程后评价两组患者的治疗效果、远期疗效和不良反应。结果(1)观察组与对照组临床观察总有效率分别为98.33%和93
2、.33%,胃镜观察总有效率分别为90.00%和86.67%,组间比较均无统计学差异。(2)治疗后，两组患者主要症状积分较治疗前均显著下降，观察组患者烧心、反酸、恶心呕吐症状积分比对照组下降显著(P<0.05)。(3)观察组肝胃不和证治愈率高于肝胃郁热、脾胃虚弱证(P<0.05)；对照组3种证型总有效率和治愈率均无显著性差异(P>0.05)o(4)观察组复发率显著低于对照组，对照组患者部分出现腹胀、轻微头痛、胃中嘈杂等不良反应。结论左金丸加味辨证与奥美拉畔联合麦滋林对反流性食管炎均有显著疗效，前者治愈率显著提高、复发率显著降低、不良反应少，对肝胃不和型证疗效
3、最佳。关键词：左金丸；辨证论治；反流性食管炎；临床研究中图分类号：R285.6；文献标志码：A文章编号：1003・9783(2016)02・doi:10.3969/j.issn.1003-9783.2016.02.TheClinicalStudyofZuojinwanModifiedDifferentialTreatmentRefluxesophagitisLiqiang-Lib2,Guifeng-Zhang1,Yiwen-Zeng12»Fang-Wang12,Jianping-Bin3,Hongyuan-Wen2,Jun-Xie，(1.ZhaoqingM
4、edicalCollege,GuangdongZhaoqing,526020；2.ZhaoqingMedicalCollegeHospitaLGuangdongZhaoqing,526020；3.ZhaoqingChineseMedicineHospitaLGuangdongZhaoqingr526020)[Abstract]Objective:ToinvestigatetheclinicalefficacyofZuojinwanmodifieddifferentialtreatmentrefluxcsophagitis.Methods:120caseso
5、frefluxesophagitiswererandomlydividedintoobservationgroupandcontrolgroup60cases.ObservationgroupusesZuojinwanmodifieddifferentialtreatment.ThecontrolgroupusesOmeprazoleandMarzulenetreatment.Evaluatethetherapeuticeffectoftwogroupsofpatients,long-termefficacyandadversereactionsafter
6、threecourses.Results:(1)Theobservationgroupandthecontrolgroup,thetotalclinicalobservationefficiencyof98.33%and93.33%respectively,thetotalefficiencyofendoscopicobservationwas90.00%and86.67%rcspcctivcly.Thcrcwerenosignificantdiflcrcnccsbetweengroups.(2)Aftcrtreatment,bothgroupsofpat
7、ientsbeforemajorsymptomscoresweresignificantlylowerthanbeforetreatment.Theobservationgroupwereheartbum,acidreflux,nauseaandvomitingsymptomscoredecreasedsignificantly(P<0.05)thanthecontrolgroup.(3)Theobservationgroupdisharmonyandthecurerateishigherthantheothertwokindsofcertificates
8、syndromes(P<0.05).Therearethreeki
