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1、中医治疗葡萄膜炎性黄斑水肿的临床疗效观察湖北十垠市医院眼科442000摘要：目的探讨中医方法治疗葡萄膜炎性黄斑水肿的临床疗效及安全性。方法选取葡萄膜炎性黄斑水肿患者23例(25眼)为研究对象，随机分为TA治疗组和中药治疗组，治疗后随访6个月期间，至少每个月检查1次，根据光学相干断层扫描(OCT)测量黄斑中心凹厚度。比较治疗前及治疗后1、3、6个月最佳矫正视力(BCVA),治疗前及治疗后6个月OCT结果，并观察治疗后6个月内并发症的发生情况。结果两组治疗后一个月，曲安奈德治疗组疗效明显优于中药治疗组，最佳矫正视力比较P<0.01,治疗后三个月对比，曲安奈德治疗组疗效明显优于中药治疗组，最佳
2、矫正视力比较P<0.05,治疗后六个月对比，中药治疗组疗效明显优于曲安奈德治疗组，最佳矫正视力比较P<0.01,OCT结果比较，中药治疗组治疗后(p=0.045)疗效明显优于TA治疗组(p=0.645)o治疗后1个月内TA治疗组仅3例(15.15%)发生眼压一过性增高，未见其他明显眼不良事件。结论益气补肾方治疗葡萄膜炎性黄斑水肿长期疗效确切，且具有较好的安全性和抗复发效应,但短期疗效低于TA治疗组。关键词：益气补肾方；葡萄膜炎；黄斑水肿中图分类号：R774文献标志码：AClinicalObservationontheTreatmentofUveitisMacularEdemawithTr
3、aditionalChineseMedicineLiuZhiObjective:ToinvestigatethetreatmentofuveitisFangQiGushenmacularedemaclinicalefficacyandsafety・Methods：Duringuveitismacularedemain23patients(25)forthestudywererandomlydividedintoTAtreatmentgroupandtreatmentgroup,werefollowedupforsixmonths,atleastonceamonthtocheck,base
4、donopticalcohereneetomographyscan(OCT)measurementoffoveaIthickness.Comparedbeforeandaftertreatment1,3,6monthsofbestcorrectedvisualacuity(BCVA),beforetreatmentandafter6monthsOCTresultswereobservedaftertheoccurrencewithin6monthsoftreatmentcomplications.Results:Afteronemonthoftreatment,triamcinoIone
5、treatmentgroupwassignificantlybetterthanthetreatmentgroup,bestcorrectedvisualacuityP<0.01,afterthreemonthsoftreatmentcomparedtriamcinoIonetreatmentgroupwassign讦icantlybetterthanthetreatmentgroup,BCVAcomparisonP<0.05,aftersixmonthsoftreatmentcomparedtreatmentgroupwassignificantlybetterthantr
6、iamcinoIoneacetonidegroup,BCVAcomparisonP<0.01,OCTresultscomparingtreatmentgroupaftertreatment(p=0.045)weresignificantlybetterthanTAtreatmentgroup(p=0.645).TAtreatmentgroupwithinamonthonly3cases(15・15%)aftertreatmentatransientincreaseofintraocularpressure,andnootherobviousocularadverseevents.C
7、onclusion:YiqiGushenTreatmentofuveitismacularedemaIong-termefficacy,andhasgoodsafetyandanti-retroviraleffect,butlowerthantheshort-termefficacyofIAtreatmentgroup.Keywords:YiqibushenFormula;uveitis;macularedema葡萄膜炎是一种容易反
