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1、中央角膜较厚的髙眼压症者临床随访观察【摘要】目的:探讨高眼压症者屮央角膜厚度(CCT)与眼压(IOP)的关系,观察CCT在判断高眼压症者是否给予降眼压治疗中的临床价值。方法:对113例(226眼)高眼压症者进行超声角膜厚度测量和非接触眼床计(NCT)测眼床,对校止眼床<21mmHg者52例(104眼)不给予降眼压药物治疗,跟踪观察其眼床、视野、生理杯和视网膜神经纤维层的变化。结杲:IOP随CCT呈正相关变化,CCT每增加100Um,IOP将随之增加1.86mmHgo对校正眼压<21mmHg者不予以降眼压治疗,跟踪观察12〜36个月,只有3例(6眼)出现视野和视神经纤维层改变,发生率为
2、2.66%(6/226)。结论:中央角膜厚度测量可以作为高眼压症与开角型青光眼进行鉴别诊断、以及判断高眼压症能否发展成为青光限的可靠依据,对高眼压症者要常规进行角膜厚度测量并校止其眼压,校止眼压<21mmHg者,可不用降眼压药物干预。【关键词】高眼压症;中央角膜厚度;校正眼压;青光眼FollowclinicalobservationofocularhypertensionofthecentralcornealthicknessCAOXian-Yong,HELin,LIYan-hua(OphthalmologyoftheThirdAffiliatedHospitalofXinxiang
3、MedicalCollegeXinxiang,Henan453003,China)[Abstract]Objective:Toinvestigateoculai*hypertensiontherelationshipbetweencentralcornealthickness(CCT)andintraocularpressure(IOP),observeCCTintheocularhypertensionanddeterminewhethertoreduceintraocularpressureclinicalvalueofthetreatment.Methods:113cases(
4、226eyes)ocularhypertensionwhowerecaniedultrasoundmeasurementofthecorneathicknessandthenon-contacttonometer(NCT)intraocularpressuremeasurement,52cases(104eyes)correctionoftheintraocularpressure<21mmHgwillnotgivepressuredrugtreatment,follow・upobservationtheintraocularpressure,visionandphysicalupa
5、ndretinalnervefiberlaye匚Results:IOPandCCTwerepositivelycoiTelatedwiththechanges,CCTforeachadditional10()μm,IOPwillincrease1.86mmHg.Correctionoftheintraocularpressure<21mmHgwillnotgivethetreatmentofocularhypertension,followedobservation12to36months,visionandopticnervefiberlayerchangesonly3cas
6、es(6eyes),incidence2.66%(6/226).Conclusions:theCentralcornealthicknessmeasurementcanbeusedasocularhypertensionandopen-angleglaucomaforthedifferentialdiagnosisandjudgeocularhypertensionwhethercanbedevelopedintoareliablebasisforglaucoma,forthosewhooftenshouldcarryoutcornealthicknessmeasurementand
7、theircorrectionIntraocularpressure,IOPcorrection<21mmHg,thereisnoneedforreduceintraocularpressuredrugs.【Keywords]OcularhypeHension;Centralcornealthickness;Correctionpressure;Glaucoma眼压(IntraocularPressure,IOP)是诊断和治疗青光眼的重要指标之一,中央角膜