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1、地诺前列酮在足刀孕妇引产中的临床对比观察［摘耍］冃的:评价普贝生(地诺前列酮)对足月孕妇引产的效果和安全性。方法:采用普贝生与缩宫素临床对比，普贝生治疗90例，缩宫素治疗60例，观察其对150例足月宫颈低评分孕妇促宫颈成熟的有效性和对产程的影响。结果:普贝牛能提高宫颈Bishop评分(2.76±1.01)分，促宫颈成熟效果达88.89%,临产时间为(19.8±10,1)h,总产程(6.8±3.1)h,剖宫产率降至16.67%,与缩宫素比较，差界有明显的统计学意义。普贝牛•和缩宫素临床使用均无严重不良反应。结论:普贝生(地诺前列酮)是一种有效
2、的促宫颈成熟和引产药物，使用方便，安全可靠。［关键词］普贝生(地诺前列酮)；阴道栓剂;促宫颈成熟;引产［中图分类号］R719.3+1［文献标识码］A［文章编号］1673-7210(2009)07(c)-077-02TheclinicalcomparisonandobservationofDinoprostonetoinducelaborintermprcgnanciosLUOYuqingl,HUANGSudan2,LIWenjiao3(1・DepartmentofGynecologyandObstetrics,Shenzhen4thPeop
3、le'sHospital(FutianDistrictHospital),Shenzhen518033,China;2.Shenzhen6thPeople'sHospital,Shenzhen518052,China;3.ChangningChildrenandMaternalHospitalofShanghai,Shanghai200051,China)［Abstract］Objective:ToevaluatetheefficicncyandsecurityofPropess(Dinoprostone)toinducelaborinte
4、rmpregnancies.Methods:WeadoptedthefunctionofOxytocinandPropesscomparative!y,90casesofPropessand60casesofOxytocinwerestudied.Theirefficiencytopromotetheripenessofcervixandtheinfluenceonthebirthprocessforthe150casesoflowcervicalscaleoftermpregnancies.Results:Propesscouldrais
5、etheBishopcervicalscaleby(2.76±1.01)scores,theefficiencytopromotetheripenessofcervixcouldreach88・89%,theparturienttimewas(19.8±10.1)hours,thetotal1aborstageswere(6.8±3<1)hours,therateofcesareanoperationdroppedto16.67%.ThedevianeewithOxytocinhadobviousstatisticalsignificanc
6、e.TheclinicalusageofPropessandOxytocinhadnoseriousadversereactions.Conclusion:Propcss(Dinoprostone)isaneffectivedrugtopromotetheripenessofcervixandinduce1abor.Ttisconvenient,safeandreliable.［Keywords］Propess(Dinoprostone);Vaginalsuppository;Promotionoftheripenessofcervix;I
7、nducelabor地诺前列酮(普贝生)缓释栓是一种较为理想的足刀妊娠引产药物。我院应用普贝生(Propess)对宫颈低评分产妇观察其促宫颈成熟(cervicalripening)的有效性及对产程(thecourseof1abour)的影响。1资料与方法1.1一般资料选取2007年6月〜2008年6月我院产科入院待产的初产妇150例，入选条件:年龄23〜35岁，孕38〜42周，单胎头位、胎膜未破，宫颈评分W6分,无阴道分娩及无前列腺素应用禁忌等，随机分为两组,研究组90例,对照组60例，两组孕妇年龄、孕周、宫颈评分及引产指征等无统计学差异。
8、1.2方法两组孕妇用药前均行阴道检杏及宫颈Bishop评分。研究组采用控释前列腺素E2(普贝生)10吨引产,在无菌条件下置入阴道后穹隆深处，留2〜3cm终止带于阴道口，用药后卧床
