Autonomic Nervous Sy

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1、AutonomicNervousSystemI.DivisionsA.SympatheticfightorflightresponseB.ParasympatheticrestanddigestionII.InvoluntaryMotorSystemA.Autonomicvs.Somaticmotorsystems1.Somaticvoluntarydirectsynapseexcitatory2.Autonomicinvoluntarydisynaptic(preganglion,postganglion)Excitatoryandinhibit

2、oryIIIGeneralnervepathwaysA.SympatheticPreganglioncellbody–graymatteraxonsmovethroughventralrootofspinalnervesynapsew/postganglionatsympatheticchainganglionaxonsofpostganglionsexitviaSpinalnerveSympatheticnerveExceptions:somepredonotsynapseatsympchainSplanchnicnerveaxonsofpreg

3、anglionexitSplanchnicnerveandsynapseatcollateralganglionw/postAdrenalglandpreganglionsynapsesdirectlyw/adrenalB.Parasympatheticcellbodiesofpreganglion–brainstem(nuclei)andsacralregionofspinalcordaxonsmovethroughcranialnervesandthroughspinalnervessynapsew/postganglionatganglian

4、earorinthetargetIV.SignaltransmissionA.SympatheticPreganglionsecretesAcetylcholine(Cholinergic)Postganglion–receptor=NicotinicPostganglionsecretesNorepinephrine(Adrenergic)Target(smoothmuscle,cardiac,glands)Receptor=Adrenergic(α,β)SweatGlandsPreganglionsecretesAcetylcholinePos

5、tganglion–nicotinicreceptorPostganglionsecretesAcetylcholineSweatgland–muscarinicreceptorB.ParasympatheticPreganglionsecretesAcetylcholine(Cholinergic)Postganglion–receptor=nicotinicPostganglionsecretesAcetylcholineTarget(Smoothmuscle,heart,glands)receptor=muscarinicV.ANSgener

6、alizedA.RegulatedB.ExcitatoryandinhibitorydependsonthetargetorganC.OppositeeffectsVI.AutonomiccontrolA.CardiovascularfunctionSympathetic:Norepinephrine-IncreasescardiacmusclecontractionsIncreasesbloodpressureParasympathetic:AcetylcholineDecreaseincardiacoutputduetodecreaseinca

7、lciuminfluxB.Pupillarylightreflex1.Parasympatheticconstrictspupil2.SympatheticDilatespupilC.Salivaryglands1.Sympatheticviscoussecretion/vasoconstrictionofbloodvessels2.Parasympatheticwaterysecretion/vasodilationofbloodvessels