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时间:2019-09-23
《超声检测颈动脉粥样硬化及其与冠心病的相关性分析》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、超声检测颈动脉粥样硬化及其与冠心病的相关性分析作者:沈敏,李兰荪,贾国良,郭文怡,王海昌【关键词】 颈动脉 (第四军医大学西京医院心血管内科,陕西西安710033) Relationshipbetweencarotidatherosclerosisandcoronaryarterydisease SHENMin,LILanSun,JIAGuoLiang,GUOWenYi, WANGHaiChang DepartmentofCardiovasology,XijingHospital,Fourt
2、hMilitaryMedicalUniversity,Xian 710033,China 【Abstract】AIM: Toevaluatetherelationshipbetweencarotidatherosclerosisandcoronaryarterydisease(CAD)byinvestigatingtheintimiamediathicknessandplaquesoncarotidarteryandtoanalyzetheriskfactorsofCAD.METHODS: Usin
3、gBmodeultrasonography,theintimiamediathicknessofcarotidarterywasmeasuredandtheriskfactorsofCADwereanalyzedinCADgroupof69patients,whoweredividedinto3subgroups(20in1vesselgroup,23in2vesselgroupand26in3vesselgroup)and21subjectswithnormalcoronaryarteriesasc
4、ontrol.RESULTS: TheintimiamediathicknessofCADgroupwassignificantlyhigherthanthatofthecontrolgroupandnosignificantdifferencewasobservedamongthe1,2and3vesselgroups.Atheroscleroticplaqueswerefoundmostlyinthecarotidbifurcationandcommoncarotidarterysegments.
5、Thediscoveryrateofatheroscleroticplaqueswashigherin2and3vesselgroups.ThecontentofTCandLDLC,andtheincidenceofhypertensionanddiabetesmellituswerehigherintheCADgroup. CONCLUSION: CADispositivelyassociatedwiththeseverityofatherosclerosisincarotidartery.Risk
6、factorsofCADcanbepredictedbycarotidultrasoundimagining. 【Keywords】carotidarteries;atherosclerosis/ultrasonography;coronary disease/ultrasonography;riskfactors 【摘要】目的:通过对颈动脉内中膜厚度(IMT)及颈动脉粥样硬化斑块的检测,探讨颈动脉粥样硬化病变的发生与冠心病的关系及其与冠心病危险因素的关系.方法:应用高频超声测定IMT及斑块的超声
7、分级,并与冠心病的多种危险因素进行分析.检测的90例患者中,经冠脉造影证实,冠心病组69例,对照组21例.结果:冠心病组中,IMT明显大于对照组,但冠脉病变组之间无差异.冠心病组的颈动脉硬化斑块的检出率明显高于对照组,且与冠脉病变的严重程度有关,以分叉部为最高,依次为颈总动脉和颈内动脉.总胆固醇(TC)、低密度脂蛋白胆固醇(LDLC)水平及高血压、糖尿病发病率在冠心病组中明显高于对照组.结论:颈动脉粥样硬化严重程度与冠心病发病率成正比.颈动脉超声可对冠心病的多种危险因素进行预测. 【关键词】 颈动脉
8、;动脉粥样硬化/超声检查;冠状动脉疾病/超声检查;危险因素 0引言 动脉粥样硬化是全身性疾病,大约99%的冠心病病因是冠状动脉粥样硬化性改变,冠脉造影作为一种有创性检查,目前还较难普及.高频超声观察颈动脉粥样硬化已广泛用于评价动脉粥样硬化的严重程度,由于其方便、安全、无创已被人们广泛接受和使用.大量研究结果表明,动脉血管内中膜增厚(intimamediathickness,IMT)是动脉粥样硬化的早期特征[1],人们日益关注颈动脉粥样硬化与冠状动脉粥
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