女性盆腔浆液性癌20例临床病理分析_石新兰_42496

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1、·286·临床与实验病理学杂志JClinExpPathol2015Mar;31(3)网络出版时间:2015－3－2316:36网络出版地址:http://www．cnki．net/kcms/detail/34．1073．Ｒ．20150323．1636．011．html女性盆腔浆液性癌20例临床病理分析石新兰，李振强，崔铁莉，李玉广，贾静，邓晓红摘要:目的探讨女性盆腔浆液性癌(pelvicserouscarcinoma，PSC)的临床病理学特征、免疫表型、发病机制及鉴别诊断。方法回顾性分析20例PSC的临床病理资料、组织学

2、形态及免疫表型，并复习相关文献。结果20例PSC，年龄23～87岁，平均58．9岁。PSC可发生于输卵管、卵巢和腹膜，常因腹胀、腹痛或盆腔占位就诊，发现时常广泛累及盆腔多个脏器，不易明确原发部位。输卵管浆液性癌原发灶小，易种植，卵巢和腹膜浆液性癌常伴有浆液性输卵管上皮内癌(seroustubalintraepithelialcarcinoma，STIC)。结论输卵管黏膜上皮细胞可能是PSC的主要来源。诊断PSC时需仔细检查输卵管以明确其原发部位，病变广泛累及腹膜时需与腹膜间皮瘤和盆腔外腺癌腹膜转移相鉴别。关键词:盆腔肿瘤

3、;浆液性癌;临床病理特征中图分类号:Ｒ737．32文献标志码:A文章编号:1001－7399(2015)03－0286－04doi:10．13315/j．cnki．cjcep．2015．03．011Pelvicserouscarcinomaoffemale:aclinicopathogicalanalysisof20casesSHIXin-lan，LIZhen-qiang，CUITie-li，LIYu-guang，JIAJing，DENGXiao-hong(DepartmentofPathology，Shijingsha

4、nTeachingHospitalofCapitalMedicalUniversity，BeijingShijingshanHospital，Beijing100043，China)Abstract:PurposeTostudytheclinicopathologicalandimmunohistochemicalfeatures，carcinogenesisanddifferentialdiagnosisoffemalepelvicserouscarcinoma．MethodsTheclinicaldata，macro

5、scopicandmicroscopicfeaturesandimmunostainingresultsof20patientswithpelvicserouscarcinomawerestudied，andsomeassociatedliteratureswerereviewed．Ｒesults20casesofPSCagedfrom23to87，withthemeanagebeing58．9．PSCmayoccurinfallopiantube，ovaryandperitoneum，whiletheywererefe

6、rredtohospitalbecauseofabdominaldistention，abdominalpainorpelvicmass．Thetumorofteninvasivepelvicorgansdiffuselywhentheywerediag-nosed，so，theprimarysiteweredifficultlydetermined．Usually，theprimaryfocusofserouscarcinomaoffallopiantubeissmallandeasilyplantedinpelvic

7、．Thepatientswithovarianserouscarcinomaorperitonealserouscarcinomahadseroustubalintraepithelialcar-cinomaatthemeantime．ConclusionsThetubalepithelialcellsmaybethemajorsourceofPSC．AboutthespecimenofPSC，weneedcheckthefallopiantubecarefullytodeterminetheprimarysite，an

8、dmakedifferentialdiagnosiswithperitonealmalignantmesothe-liomaandmetastaticcarcinomafromothersitesthanpelvicwhenitdiffuselyinvasiveperitoneum．Keywords:pelvicne