血液灌流床旁抢救急性药物及毒物中毒患者的疗效分析

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1、血液灌流床旁抢救急性药物及毒物中毒患者的疗效分析高瑞筠内江市资中县人民医院急诊科四川资中641200【摘要】目的：分析血液灌流床旁抢救急性药物及毒物中毒患者的疗效。方法：将我院收治的68例急性药物及毒物中毒患者随机分为观察组34例和对照组34例。对照组患者行常规急救方案治疗，观察组患者在常规治疗的基础上行血液灌流床旁抢救治疗。统计2组患者的救治成功率、昏迷时间；于2组患者治疗前后，采用序贯器官衰竭评分(SOFA)评价患者的器官衰竭情况，采用快速急诊内科评分(REMS)评价患者的病情危重程度，并检测患者血

2、清肿瘤坏死因子α(TNF-α)及白细胞介素8(IL-8)的表达水平。结果：观察组患者的救治成功率为91.18%,高于对照组的73.53%(P<0.05)；观察组患者的平均昏迷时间为(8.72±1.32)h,短于对照组的(13.05±2.75)h(P<0.05)o治疗后12h、24h,观察组患者的平均SOFA评分与REMS评分均低于对照组(P<0.05)o治疗后48h,观察组患者的平均血清TNF-α>IL-8指标值均低于对照组(PV0.05)

3、。结论：在常规治疗的基础上行血液灌流床旁抢救能有效提高急性药物及毒物中毒的救治成功率，值得临床推广应用。【关键词】急性中毒；血液灌流；急救【中图分类号1R595.4【文献标识码】B【文章编号11674-8999(2015)8-0236-02Analysisofcurativeeffectofflowbedrescueacutedrugandpoisonintoxicationpatientswithbloodperfusion[Abstract]objective:toanalyzecurativeef

4、fectofflowbedrescueacutedrugandpoisonintoxicationpatientswithbloodperfusion.Methods:68casesofacutedrugandpoisonintoxicationpatientsofourhospitalwererandomlydividedintotheobservationgroup(34cases)andthecontrolgroup(34cases).Patientsofthecontrolgroupweretr

5、eatedbyconventionalemergencyplan,onthebasisofconventionaltreatment,thepatientsofobservationgroupweretreatedbycurrentbedsideemergencytreatmentbloodperfusion.2groupsofpatientswithsuccessrate,comatimewerestatistics;beforeandaftertreatment,patientswithorganf

6、ailurewereevaluatedbysequentialorganfailureassessment(SOFA),patientswithSeverityofillnesswereevaluatedbyrapidemergencymedicinescore(REMS),thepatient'sserumtumornecrosisfactoralpha(TNF-alpha)andInterleukin8(IL-8)levelswasdetected.Results:theobservationgro

7、upofpatientstreatmentsuccessratewas91.18%,higherthanthatofcontrolgroupwith73.53%(P<0.05);Observationgroupofpatientswithaveragecomatimewas(8.72+1.32)h,shorterthanthecontrolgroupwith(13.05+2.75)h(P<0.05).12h,24haftertreatment,theobservationgroupofpat

8、ientswithaverageSOFAscoreandREMSscoreswerelowerthanthatofcontrolgroup(P<0.05).48haftertreatment,theobservationgroupofpatientswithanaverageserumTNFalpha,IL-8indexeswerelowerthanthecontrolgroup(P<0.05).Conclusion:onthe