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1、HindawiPublishingCorporationCaseReportsinUrologyVolume2014,ArticleID508305,4pageshttp://dx.doi.org/10.1155/2014/508305CaseReportAbirateroneAcetateandCastrationResistantDuctalAdenocarcinomaoftheProstateEdgarLinden-Castro,MarcelaPelayo-Nieto,AlejandroAlias-Melgar,DanielE
2、spinosa-Perezgrovas,IvanRamirez-Galindo,andGabrielCatalan-QuintoUrologyDepartment,CentroMedicoNacional20deNoviembre,FelixCuevas540,DelValle,BenitoJu´arez,´03229CiudaddeMexico,DF,Mexico´CorrespondenceshouldbeaddressedtoEdgarLinden-Castro;eall9@hotmail.comReceived25Janua
3、ry2014;Revised7April2014;Accepted15April2014;Published7May2014AcademicEditor:ChristianPavlovichCopyright©2014EdgarLinden-Castroetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense,whichpermitsunrestricteduse,distribution,andreproductionina
4、nymedium,providedtheoriginalworkisproperlycited.Ductaladenocarcinomaoftheprostateisararehistologicalvariantthatonlyrepresents<1%ofprostatetumors.Thishistologicalvarianthasseveralimportantclinicalimplicationswithrespecttotheirevolution,clinicalprognosis,andtreatment.Wer
5、eportthecaseofa64-year-oldpatientwithductaladenocarcinomaoftheprostate,whichprogressestocastration-resistantprostatecancer,thatwastreatedwithabirateroneacetatewithgoodclinicalresponse,toourknowledge,thefirstcaseofductaladenocarcinomaoftheprostateintreatmentwithabirater
6、oneacetate.1.Introductioncurrentconditionin2007withurinaryvoidingandstoragesymptoms,progressingtoacuteurinaryretention.FromthatProstatecancerisadiseasewithavariableclinicalcourse.indication,weperformedaTURP,obtainingprostatetissueHistorically,Gleasonscoreisanimportantf
7、actorinriskwithnoevidenceofmalignancy.Elevenmonthsaftrthesur-stratification.Theroleofthetreatmentandprognosisofgicalevent,hedevelopeddysuriaandintermittentepisodesnonacinarhistologicalvariantsofprostatecancerisknownofgrosshaematuriaaccompaniedbyelevatedprostate-fromsom
8、evariants,whilenotforothersyet.Ductaladeno-specifiantigenlevels(9.3ng/mL);weperformedatran-carcinomaoftheprostateisah
