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1、Anal.Chem.2009,81,23032310ParticleTrappinginHigh-ConductivityMediawithElectrothermallyEnhancedNegativeDielectrophoresisSeungkyungPark,MehtiKoklu,andAliBeskok*AerospaceEngineeringDepartment,OldDominionUniversity,Norfolk,Virginia23529Wedemonstratenegati
2、vedielectrophoresis(DEP)trap-Activecontrolofcolloidalmotioncanbeachievedthroughthepingofparticlesfromhigh-conductivitymediausingaapplicationofavarietyofphysicalforces,includingmechanical,4novelplanarmicroelectrodethatallowselectrothermalfluidic,optical
3、,acoustic,electrokinetic,andelectromagnetic.enhancementofDEPtraps.DEPforceandelectrothermalAmongtheseforces,dielectrophoresis(DEP)hasseveraladvan-flowmotionareinvestigatedusingascalinganalysis,tagessuchasremotemanipulationofparticlesbyelectricfieldnumer
4、icalsimulations,andexperiments.Resultsshowcontrolandsimpleconfigurationofdeviceswithoutmechanical5thattheDEPtrappingisenhancedbylateraltransportofmovingcomponents.DEPisthemotionofpolarizableparticlesparticlestowardthecapturezonesduetoelectrothermalthat
5、aresuspendedinanionicsolutionandsubjectedtoaspatiallyflow,whereasDEPtrappingoccurredonlyinlimitednonuniformelectricfield.Whenthepolarizabilityoftheparticlesspatialrangeswithouttheflowmotion.Theelectrother-islargerthanthatofthefluid,theparticlesmovetowardr
6、egionsmallyenhancedDEPwillbroadenthelimitofelectroki-ofthehighelectricfielddensity(positiveDEP).Ifthefluidisneticmanipulationsinhigh-conductivitymedia.Bypro-morepolarizablethantheparticles,theparticlesmoveawayfromvidingpatternedtrappingzonesthatcanactas
7、target-thehighelectricfielddensity(negativeDEP).Itispossibletospecificattachment/detectionsites,thepresenteddeviceinducefrequency-specificvariationsinparticlepolarizabilityusingallowsdevelopmentofbiosensorapplicationsforrapidacelectricfields,whichfurthere
8、nrichestherealmofDEPdetectionofpathogensandothermicroorganismswithinapplications.apracticalrangeofbufferconductivity.PositiveDEPhasbeenutilizedfortrappingandseparatingcolloidalparticlesbyseveralresearchersusinginterdigitated,grid,6point-and-li
