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《The Role of Subchondral Bone in Joint Disease软骨下骨在关节疾病中的作用》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、ReprintedintheIVISwebsitewiththepermissionofAAEPClosewindowtoreturntoIVISINDEPTH:CURRENTCONCEPTSINEQUINEOSTEOARTHRITISTheRoleofSubchondralBoneinJointDiseaseChristopherE.Kawcak,DVM,PhD,DiplomateACVS;C.WayneMcIlwraith,BVSc,PhD,FRCVS,DiplomateACVS;RichardD.Park,DVM,PhD;andS.P.James,PhDThereis
2、evidencetosuggestthatosteochondraldiseasesintheathletichorsestartaschronicprocesseswhichculminateinclinicaldisease.Authors'addresses:EquineOrthopaedicResearchLaboratory(KawcakandMcIlwraith),DepartmentofRadiologicalHealthSciences(Park),CollegeofVeterinaryMedicineandBiomedicalSciences,andDep
3、artmentofMechanicalEngineering(James),CollegeofEngineering,ColoradoStateUniversity,FortCollins,CO80523.©2001AAEP.1.IntroductionderstandingofosteochondraldiseaseisbasedonSubchondralboneplaysaroleinthepathogenesisofclinicalandpathologicsources,andthatthelackofosteochondraldamageandosteoarthr
4、itisinhorsesinformationaboutjointtissueadaptationanddis-andhumans.Osteochondralfragmentationandeasehashamperedobjectivestudiesofosteochon-draltissues.fracture,subchondralbonenecrosis,andosteoar-thritisarecommondiseasesinathletichorses,andsubchondralboneisnowthoughttoplayanintegral2.Osteoch
5、ondralTissuesroleinthepathogenesisofthesediseases.ThereThetissuesthatcomposeandsupportjointsurfaceshavebeennumerousresearcheffortsfocusedonar-arecollectivelycalledosteochondraltissues.Theticularcartilagedamageanditspathogenesis,yetmostsuper®cialofthese,thearticularcartilage,iscomparatively
6、littleefforthasbeenfocusedonsub-essentialforabsorbingshockandmaintainingnor-chondralbonepathology,orthecoordinateddiseasemaljointenvironment,and,regardlessofthecause,statesoftheosteochondraltissues.Thepurposeofdegenerationofarticularcartilagecanresultinir-1thisreportistoreviewthecurrentund
7、erstandingreversibleosteoarthritis.Thesubarticulartissuesofosteochondraldiseaseinallspeciesanditsap-includecalci®edcartilage,whichprovidesatransi-plicationtoequineresearchandpractice.Itcanbetionbetweenthestiffsubchondralboneandtheconcludedfromthisreviewthatour
