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1、Ovid:Intraoperativeevaluationoftissueperfusioninhigh-riskpatientsbyinvasivean...Page1of15CriticalCareMedicineIssue:Volume27(10),October1999,pp2147-2152Copyright:©1999LippincottWilliams&Wilkins,Inc.PublicationType:[ClinicalInvestigations]ISSN:0090-3493Accession:00003246-199910000-00012Keywords:h
2、igh-risksurgicalpatients,intraoperativehemodynamicmonitoring,survivorandnonsurvivorpatterns,thoracicbioimpedanceestimationofcardiacoutput,pulseoximetry,transcutaneousoxygenandcarbondioxide,oxygenconsumption,multicomponentnoninvasivecirculatorymonitoring,earlydiagnosisofshockandorganfailure[Clin
3、icalInvestigations]Intraoperativeevaluationoftissueperfusioninhigh-riskpatientsbyinvasiveandnoninvasivehemodynamicmonitoringShoemaker,WilliamC.MD,FCCM;Thangathurai,DuraiyahMD,FCCM;Wo,CharlesC.J.BS;Kuchta,KennethMD;Canas,MarcosMD;Sullivan,MichaelJ.MD;Farlo,JosephMD;Roffey,PeterMD;Zellman,Vladimi
4、rMD;Katz,RonaldL.MDAuthorInformationFromtheDepartmentsofAnesthesiology(Drs.Shoemaker,Thangathurai,Kuchta,Canas,Sullivan,Farlo,Roffey,Zellman,andKatzandMr.Wo)andSurgery(Dr.ShoemakerandMr.Wo),UniversityofSouthernCaliforniaSchoolofMedicine,LosAngeles,CA.Addressrequestsforreprintsto:WilliamC.Shoema
5、ker,MD,LosAngelesCountyandUniversityofSouthernCaliforniaSchoolofMedicine,1200N.StateStreet,Room9900,LosAngeles,CA90033.AbstractObjective:Althoughinvasivemonitoringhasnotbeeneffectiveinlatestagesafterorganfailurehasoccurred,earlypostoperativemonitoringrevealeddifferencesinsurvivorandnonsurvivorp
6、atternsandprovidedgoalsforimprovingoutcome.Wesearchedfortheearliestdivergenceofsurvivorandnonsurvivorcirculatorychangesasanapproachtoearlierpreventivetherapy.Theaimwastodescribetheintraoperativetimecourseofcirculatorydysfunctioninsurvivorsandnonsurvivorsamonghigh-riskelectivesurgerypatientsusin
7、gboththethermodilutionpulmonaryarterycatheter(PAC)andmulticomponentnoninvasivemonitoring.Design:Prospectiveintraoperativedescriptionofcirculatorydysfunction.Setting:University-runcountyhospital.Patients:Twohundrednineconsecutively