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1、NEURALREGENERATlONRESEARCHVolume8，Issue3，Janua~2013doi：lO．3969~'．issn．1673—5374．2013．03．001lh挂p：／／www．nrronline．org；h#p：llwww．sjzsyj．org]J#7YL．DongLY,WuCQQ#7J．LiS．WangCY,ShaoX．HuangDK．BuyangHuanwuDecoctionfractionprotectsagainstcerebralischemia／reper
2、fusioninjurybyafenua~ngtheinflammatoryresponseandcelularapoptosis，NeuralRegenRes．2013；8(3,l：197-207tectsagainst，一0■●0■■一■■■-CerebrallschemIa／reperfusIonlnlurybyattenuating1一theinflammatoryresponseandcellularapoptosis★★YulianJin’，2LiuyiDong’ChangqingW
3、u’JiangQin’，ShengLi’，ChunyanWang。，XuShao4，j，，DakeHuang1DepartmentofPharmacology,KeyLaboratoryofAnti-inflammatoryandImmunopharmacology,M#7~tryofEducation；KeyLaboratoryofCh
4、neseMedicineResearchandDevelopment,StateAdministrationofTra~tionalChineseMedici
5、neAnhuiMedicalUniversity,Hefe
6、230032，AnhuiPrevince，China2AnhuiProvincialChfldrensHospita1．Hefe
7、230051AnhuiProvince．China3AnhuiInstituteofMateriaMedica，怡ref230022，AnhuiProv#Tce．China4Hefe
8、Qi-x#TgMedicineandTechnoIogYCoLtd，．Hefei230088．AnhuiProvince．Ch
9、ina5SyntheticLaboratoryofBasicMedicineCollege，AnhuiMedicalUniversity,Hefef230032，AnhuiProvince，ChinaAbstractBuyangHuanwuDecoctionfractionextractedfr0mBuyangHuanwuDecoctioncontainssaponinsofYulianJin★．Master．Chiefphysician，Master’sAstragalus，totalpaeo
10、nyglycosideandsaflowerflavones．Theaimofthisstudywastodemonstratesupervisor．theneuroprotectiveeffectandmechanismofBuyangHuanwuDecoctionfractiononischemicinjuryYulianJinandLiuyiDongboth『门vivoandinvitro．Invivoexperimentsshowedthat50-200mg／kgBuyangHuanwu
11、Decoctioncontributedequallytothisfractionreducedinfarctvolumeandpathologicalinjuryinischemia／reperfusionrats，markedlyworkinhibitedexpressionofnuclearfactOr-KBandtumornecrosisfactor-aandpromotednestinproteinCorrespondingauthor：Liuyiexpressioninbrainti
12、ssue．BuyangHuanwuDecoctionfraction(200mg／kg)exhibitedsignificantDong．PhD，MD，Associateprofessor,Departmentofefects．whichweresimilartothoseof100mg／kgGinkgobilobaextract．InvitroexperimentalresultsPharmacology,Keydemonstratedthat10—1O0mg／LBuyangHuanwuDec
