资源描述：
《1. Comparison of frequency and time domain methods of assessment of cerebral autoregulation in traumatic brain injury 英文学习材料》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、JournalofCerebralBloodFlow&Metabolism(2015)35,248–256©2015ISCBFMAllrightsreserved0271-678X/15$32.00www.jcbfm.comORIGINALARTICLEComparisonoffrequencyandtimedomainmethodsofassessmentofcerebralautoregulationintraumaticbraininjury11,21111,34XiuyunLiu,MarekCzosnyka,JosephDonnelly,K
2、arolPBudohoski,GeorgiosVVarsos,NathalieNasr,KenMBrady,511MatthiasReinhard,PeterJHutchinsonandPeterSmielewskiTheimpulseresponse(IR)-basedautoregulationindex(ARI)allowsforcontinuousmonitoringofcerebralautoregulationusingspontaneousfluctuationsofarterialbloodpressure(ABP)andcerebr
3、alflowvelocity(FV).Wecomparedthreemethodsofautoregulationassessmentin288traumaticbraininjury(TBI)patientsmanagedintheNeurocriticalCareUnit:(1)IR-basedARI;(2)transferfunction(TF)phase,gain,andcoherence;and(3)meanflowindex(Mx).AutoregulationindexwascalculatedusingtheTFestimation(W
4、elchmethod)andclassifiedaccordingtotheoriginalTiecks’model.Mxwascalculatedasacorrelationcoefficientbetween10-secondaveragesofABPandFVusingamoving300-seconddatawindow.Transferfunctionphase,gain,andcoherencewereextractedintheverylowfrequency(VLF,0to0.05Hz)andlowfrequency(LF,0.05to
5、0.15Hz)bandwidths.Westudiedtherelationshipbetweentheseparametersandalsocomparedthemwithpatients’Glasgowoutcomescore.Thecalculationswereperformedusingbothcerebralperfusionpressure(CPP;suffix‘c’)asinputandABP(suffix‘a’).TheresultshowedasignificantrelationshipbetweenARIandMxwhenusin
6、geitherABP(r=−0.38,Po0.001)orCPP(r=−0.404,Po0.001)asinput.Transferfunctionphaseandcoherence_aweresignificantlycorrelatedwithARI_aandARI_c(Po0.05).OnlyARI_a,ARI_c,Mx_a,Mx_c,andphase_cweresignificantlycorrelatedwithpatients’outcome,withMx_cshowingthestrongestassociation.JournalofC
7、erebralBloodFlow&Metabolism(2015)35,248–256;doi:10.1038/jcbfm.2014.192;publishedonline19November2014Keywords:cerebralautoregulationindex;meanflowindex;transcranialdoppler;transferfunctionanalysisINTRODUCTIONparameters(frequencydependent):TFphase,gain,andCerebralpressureautoregu
8、lation(CA)referstotheabilityofcoherence.cerebralarterialblood
