17-90 [6.19]TiO2-Nanowired Delivery of DL-3-n-butylphthalide (DL-NBP) Attenuates Blood-Brain Barrier Disruption, Brain Edema Formation, and Neuronal Damages Following Concussive Head Injury

《17-90 [6.19]TiO2-Nanowired Delivery of DL-3-n-butylphthalide (DL-NBP) Attenuates Blood-Brain Barrier Disruption, Brain Edema Formation, and Neuronal Damages Following Concussive Head Injury》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、TiO2-NanowiredDeliveryofDL-3-n-butylphthalide(DL-NBP)AttenuatesBlood-BrainBarrierDisruption,BrainEdemaFormation,andNeuronalDamagesFollowingConcussiveHeadInjuryLianyuanFeng,ArunaSharma,FengNiu,YinHuang,JoséVicenteLafuente,DafinFiorMuresanu,AsyaOzkizilcik,Z. RyanTian,etal.Molecul

2、arNeurobiologyISSN0893-7648MolNeurobiolDOI10.1007/s12035-017-0746-5123YourarticleisprotectedbycopyrightandallrightsareheldexclusivelybySpringerScience+BusinessMedia,LLC.Thise-offprintisforpersonaluseonlyandshallnotbeself-archivedinelectronicrepositories.Ifyouwishtoself-archivey

3、ourarticle,pleaseusetheacceptedmanuscriptversionforpostingonyourownwebsite.Youmayfurtherdeposittheacceptedmanuscriptversioninanyrepository,provideditisonlymadepubliclyavailable12monthsafterofficialpublicationorlaterandprovidedacknowledgementisgiventotheoriginalsourceofpublicati

4、onandalinkisinsertedtothepublishedarticleonSpringer'swebsite.Thelinkmustbeaccompaniedbythefollowingtext:"Thefinalpublicationisavailableatlink.springer.com”.123Author'spersonalcopyMolNeurobiolDOI10.1007/s12035-017-0746-5TiO2-NanowiredDeliveryofDL-3-n-butylphthalide(DL-NBP)Attenu

5、atesBlood-BrainBarrierDisruption,BrainEdemaFormation,andNeuronalDamagesFollowingConcussiveHeadInjury12,3,544LianyuanFeng&ArunaSharma&FengNiu&YinHuang&5,8,96,71011JoséVicenteLafuente&DafinFiorMuresanu&AsyaOzkizilcik&Z.RyanTian&2,3,5HariShankerSharma#SpringerScience+BusinessMedia

6、,LLC2017AbstractDL-3-n-butylphthalide(DL-NBP)isoneoftheneuronalinjuries.Themagnitudeandintensityofthesepath-constituentsofChineseceleryextractthatisusedtotreatologicalchangesweremostmarkedinthelefthemisphere.stroke,dementia,andischemicdiseases.However,itsroleinTreatmentwithDL-N

7、BPsignificantlyreducedbrainpatholo-traumaticbraininjuryislesswellknown.Inthisinvestigation,gyinCHIfollowing8to12hat40-mgdose.However,60-mgneuroprotectiveeffectsofDL-NBPinconcussiveheadinjurydoseisneededtothwartbrainpathologyat24hfollowing(CHI)onbrainpathologywereexploredinaratm

8、odel.CHICHI.Ontheotherhand,TiO2-DL-NBPwaseffectiveinre