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1、SleepMedicine15(2014)742–748ContentslistsavailableatScienceDirectSleepMedicinejournalhomepage:www.elsevier.com/locate/sleepOriginalArticleObstructivesleepapneaisassociatedwithcancermortalityinyoungerpatientsa,n,⇑bc,nMiguelA.Martínez-García,FranciscoCa
2、mpos-Rodriguez,JoaquínDurán-Cantolla,d,ne,nfg,nhMónicadelaPeña,MaríaJ.Masdeu,MónicaGonzález,FélixdelCampo,PabloCatalánSerra,aaij,nk,nIreneValero-Sánchez,M.J.SelmaFerrer,JoséM.Marín,FerránBarbé,M.Martínez,l,nm,nRamónFarré,JoséM.Montserrat,onbehalfofthe
3、SpanishSleepNetworkaRespiratoryDepartment,LaFeUniversityandPolytechnicHospital,Valencia,SpainbRespiratoryDepartment,ValmeUniversityHospital,Sevilla,SpaincAlavaUniversityHospital,Vitoria,SpaindRespiratoryDepartment,SonEspasesUniversityHospital,PalmadeM
4、allorca,SpaineRespiratoryDepartment,CorporacióSanitariaParcTauliHospital,Sabadell,SpainfRespiratoryDepartment,MarquesdeValdecillaHospital,Santander,SpaingRespiratoryDepartment,RioHortegaHospital,Valladolid,SpainhRespiratoryUnit,RequenaGeneralHospital,
5、Valencia,SpainiRespiratoryDepartment,MiguelServetHospital,Zaragoza,SpainjRespiratoryDepartment,ArnaudeVilanovaHospital,IRB,Lleida,SpainkIRBLleida,Lleida,SpainlFacultatdeMedicina,UniversitatdeBarcelonaUniversity,IDIBAPS,SpainmRespiratoryDepartment,Clin
6、icHospital–IDIBAPS,Barcelona,SpainnCIBERdeEnfermedadesRespiratorias,Bunyola,SpainarticleinfoabstractArticlehistory:Objective:Theassociationbetweenobstructivesleepapnea(OSA)andcancermortalityhasscarcelybeenReceived30July2013studied.Theobjectiveofthisst
7、udywastoinvestigatewhetherOSAisassociatedwithincreasedcancerReceivedinrevisedform15January2014mortalityinalargecohortofpatientswithOSAsuspicion.Accepted17January2014Methods:ThiswasamulticenterstudyinconsecutivepatientsinvestigatedforsuspectedOSA.OSAAv
8、ailableonline15May2014severitywasmeasuredbytheapnea–hypopneaindex(AHI)andthehypoxemiaindex(%night-timespentwithoxygensaturation<90%,TSat90).TheassociationbetweenOSAseverityandcancermortalitywasKeywords:assessedusingCox’sproportionalregressiona