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1、TargetedTherapiesinCancer:MythorReality?ADVANCESINEXPERIMENTALMEDICINEANDBIOLOGYEditorialBoard:NATHANBACK,StateUniversityofNewYorkatBuffaloIRUNR.COHEN,TheWeizmannInstituteofScienceABELLAJTHA,N.S.KlineInstituteforPsychiatricResearchJOHND.LAMBRIS,Universi
2、tyofPennsylvaniaRODOLFOPAOLETTI,UniversityofMilanRecentVolumesinthisSeriesVolume602OSTEOIMMUNOLOGY:INTERACTIONSOFTHEIMMUNEANDSKELETALSYSTEMSEditedbyYongwonChoiVolume603THEGENUSYERSINIA:FROMGENOMICSTOFUNCTIONEditedbyRobertD.PerryandJacquelineD.FethersonV
3、olume604ADVANCESINMOLECULARONCOLOGYEditedbyFabriziod’AddadiGagagna,SusannaChiocca,FraserMcBlaneandUgoCavallaroVolume605INTEGRATIONINRESPIRATORYCONTROL:FROMGENESTOSYSTEMSEditedbyMarcPoulinandRichardWilsonVolume606BIOACTIVECOMPONENTSOFMILKEditedbyZsuzsann
4、aBoszeVolume607EUKARYOTICMEMBRANESANDCYTOSKELETON:ORIGINSANDEVOLUTIONEditedbyGáspárJékelyVolume608BREASTCANCERCHEMOSENSITIVITYEditedbyDihuaYuandMien-ChieHungVolume609HOTTOPICSININFECTIONANDIMMUNITYINCHILDRENVIEditedbyAdamFinnandAndrewJ.PollardVolume610T
5、ARGETEDTHERAPIESINCANCEREditedbyFrancescoColottaandAlbertoMantovaniAContinuationOrderPlanisavailableforthisseries.Acontinuationorderwillbringdeliveryofeachnewvolumeimmediatelyuponpublication.Volumesarebilledonlyuponactualshipment.Forfurtherinformationpl
6、easecontactthepublisher.FrancescoColottaAlbertoMantovaniEditorsTargetedTherapiesinCancer:MythorReality?FrancescoColottaAlbertoMantovaniNervianoMedicalSciencesIstitutoClinicoHumanitasand10VialePasteurInstituteofPathologyNerviano(Milano)20014,ItalyUnivers
7、ityofMilanfrancesco.colotta@nervianoms.com56ViaManzoniRozzano,Milano20089,Italyalberto.mantovani@humanitas.itISBN978-0-387-73897-0e-ISBN978-0-387-73898-7LibraryofCongressControlNumber:2007936362©2008SpringerScience+BusinessMedia,LLCAllrightsreserved.Thi
8、sworkmaynotbetranslatedorcopiedinwholeorinpartwithoutthewrittenpermissionofthepublisher(SpringerScience+BusinessMedia,LLC,233SpringStreet,NewYork,NY10013,USA),exceptforbriefexcerptsinconnectionwithreviewsorscholarlyanalysis.Usein