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1、ScienceandTechnologyofAdvancedMaterialsISSN:1468-6996(Print)1878-5514(Online)Journalhomepage:http://www.tandfonline.com/loi/tsta20Biodegradableorganicacid-crosslinkedalkali-treatedgelatinswithanti-thrombogenicandendothelializationpropertiesMotokiInoue,MakotoSasaki&TetsushiTaguchiTocitethisarticle:
2、MotokiInoue,MakotoSasaki&TetsushiTaguchi(2012)Biodegradableorganicacid-crosslinkedalkali-treatedgelatinswithanti-thrombogenicandendothelializationproperties,ScienceandTechnologyofAdvancedMaterials,13:6,064215,DOI:10.1088/1468-6996/13/6/064215Tolinktothisarticle:https://doi.org/10.1088/1468-6996/13
3、/6/064215©2012NationalInstituteforMaterialsSciencePublishedonline:13Dec2012.SubmityourarticletothisjournalArticleviews:1041FullTerms&Conditionsofaccessandusecanbefoundathttp://www.tandfonline.com/action/journalInformation?journalCode=tsta20IOPPUBLISHINGSCIENCEANDTECHNOLOGYOFADVANCEDMATERIALSSci.Te
4、chnol.Adv.Mater.13(2012)064215(9pp)doi:10.1088/1468-6996/13/6/064215Biodegradableorganicacid-crosslinkedalkali-treatedgelatinswithanti-thrombogenicandendothelializationpropertiesMotokiInoue1,MakotoSasaki1,2andTetsushiTaguchi1,21BiomaterialsUnit,Nano-LifeField,InternationalCenterforMaterialsNanoarc
5、hitectonics(MANA),NationalInstituteforMaterialsScience(NIMS),1-1Namiki,Tsukuba,Ibaraki305-0044,Japan2GraduateSchoolofPureandAppliedScience,UniversityofTsukuba305-8577,JapanE-mail:TAGUCHI.Tetsushi@nims.go.jpReceived24July2012Acceptedforpublication8November2012Published13December2012Onlineatstacks.i
6、op.org/STAM/13/064215AbstractGelatinswerecrosslinkedwithorganicacidsandtreatedwithalkalitoimparttothemendothelializationandanti-thrombogenicproperties.Thesematriceswerecharacterizedbybiochemicalandphysicochemicaltechniques.Theamountsofresidualaminogroupsinthematricesdecreasedwithincreasingcrosslin
7、kerconcentration.Thematriceswiththehighestcrosslinkingdensitiesshowedexcellentendothelialcelladhesionandproliferation.Inaddition,theadhesionofplateletsandformationoffibrinnetworksonthematricesweresuppressedwithinc
