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《前列腺增生和前列腺癌的MRI和MRS表现_田志雄》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、DOI:10.13437/j.cnki.jcr.2003.12.010·1022·临床放射学杂志2003年第22卷第12期腹部放射学前列腺增生和前列腺癌的MRI和MRS表现田志雄,孙骏谟,吴光耀,黄雄,屈艳娟【摘要】目的分析良性前列腺增生(BPH)和前列腺癌(PC)的MR和MRS的表现,探讨MRS在前列腺病变诊断中的价值。资料与方法回顾分析经病理证实的27例(BPH17例,PC10例)患者的临床资料及MRI和MRS所见。MRI分析指标为前列腺大小和形态、病变位置、信号特点和肿瘤侵犯程度。MRS观察枸橼酸盐(Citr)和胆碱复合物(Cho)化学位移及其比值。结果
2、12例(12/17,70.6%)BPHT1WI上前列腺不规则增大,呈均匀的低信号,5例(5/17,29.4%)前列腺大小、形态正常;T2WI上前列腺中央腺体显著增大,与外周带高信号分界清楚,14例(82.4%)增生腺体表现为多个大小不等的圆形低信号和高信号结节灶,3例(17.6%)表现为弥漫性低信号;MRS上Citr波峰升高,Citr/Cho比值增大。10例PCT2WI上高信号外周带内见局灶性低信号区;4例位于前列腺包膜内,6例前列腺包膜受累,3例侵犯精囊,2例侵犯血管神经束,1例侵犯膀胱,1例盆腔内见多个肿大淋巴结,部分相互融合成块。MRS上Citr峰明显下
3、降,Cho峰升高,Citr/Cho比值明显下降,与BPH比较有显著性差异(P<0.05)。结论MRI能很好地反映BPH特点和判断PC包膜内、外受累;MRS能提供前列腺组织的代谢信息有助于鉴别PC和BPH。【关键词】良性前列腺增生前列腺癌磁共振成像磁共振波谱BenignHyperplasiaandCarcinomaofProstateGland:MRImagingandMRSpectroscopyFindingsTIANZhixiong,SUNJunmo,WUGuangyao,etal.MedicalImagingCenter,ZhongnanHospital,
4、WuhanUniversity,Wuhan,HubeiProvince430071,P.R.China【Abstract】ObjectiveTodescribeMRimaging(MRI)andspectroscopic(MRS)appearancesofbenignhyperplasiaandcarci-nomaoftheprostate,andtoevaluateMRSinthediagnosisofprostatediseases.MaterialsandMethodsClinicaldatatogetherwithMRIandMRSfindingswe
5、rereviewedretrospectivelyin27patientswithpathologically-confirmedprostatediseases,whichin-cluded17caseswithbenignprostatehyperplasia(BPH)and10caseswithprostatecarcinoma(PC).MRIobservationwasfocusedonthesizeofthegland,thelocationofthelesion,thesignalfeaturesandtheextentofthetumor.MRS
6、observationincludedthechemicalshiftofcitrate(Citr)andcholine(Cho)spectra,andtheratioofCitr/Cho.ResultsOnT1WI,irregularenlargementoftheprostateglandwithhomogeneouslow-signalwasfoundin12BPH(70%),whilein5cases(30%)theglandshowednor-malsizeandcontour.OnT2WI,markedenlargementofthecentral
7、partoftheglandwithwell-definedhigh-signalperipheralzonewasseeninall17casesofBHP,in14(82.4%)ofwhichthehyperplasiapresentedasseveraldifferent-sizedroundlow-signalorhigh-signalnodularlesions.Intheremaining3cases(17.6%),thelesionswerecharacterizedbydiffuselowsignal.OnMRS,elevatedCitrpea
8、kwithincreasedCitr/
