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1、Firstsection:Bloodroutinetest(BRT)HasSomeonehereeverheardofBRTbefore?Yes!Verygoodmanystudentshaveheardbefore.(NO?maybeyouareallveryhealthy).whenyougotohospital,doctorsalwaysapplyforaBRTasareferencetoyourdisease.Theycanknowabouttheredbloodcells,whitebloodcellsandplateletset,al.SoBRTisthemostcom
2、monexaminationinclinicallaboratory.Todaywewilllearnthebloodroutinetest(theabbreviationisBRT)orcompletebloodcount(CBC).1.Samplecollectingfirst,wewilllearnaboutthecollectionofBRTsample.Thebloodcanbecollectedfromfingerorvein.Butwearealwayscollectingbloodfromvein,Becausetheresultcomefromaveinsampl
3、eismoreaccurateandstablethanfromfinger.Butifitisverydifficulttofindagoodveintocollect,forexample,whenwemeetwithababy.Afterwecollectedthesample,thebloodmustbeanticoagulatedwithEDTA-K2.Becausewewillcountcellsinit.Wewilllearninthelater.Herepleaseremembertheanticoagulant----EDTA-K2.OK,letstakealoo
4、kofthemaincontentsofBRT.Itconcludethreeparts,theyareRBC,WBC,PLT.Nowwewilllearnonebyone.2.RBCrelatedparametersAtfirst,willlearnabouttheredbloodcells.Therearesevenparametersrelatedtoit.Theyare:1)Thenumberofredbloodcells(RBC)2)Theamountofhemoglobinintheblood(Hb)3)Hematocrit(Hct)4)meancorpuscularv
5、olume(MCV)5)Meancorpuscularhemoglobin(MCH)6)Meancorpuscularhemoglobinconcentration(MCHC)7)Redbloodcellvolumedistributionwidth(RDW)1)RBCandHbNow,letslearnaboutRBCandhemoglobin.weputthetwoindexestogether,becausetheyhavethesameclinicalsignifcance.(1)ThenormalvaluesThenormalvaluesofRBCistomale:the
6、normalnumberofRBCis4.0-5.5,toFemale:is3.5-5.0millionmillionsperliter.soitisdifferentbetweenmaleandfemale.FamiliartoRBC,thenormalvalueofhemoglobinisdifferentbetweenmaleandfemaletoo.Allthevaluesabovearerequiredtoremember.ThenumbersofRBCortheconcentrationsofHbisincreased,itcanbecausedbyrelativefa
7、ctorsorabsolutelyfactors.Forexample,whenwesickingburningorsweatingtoomuch,muchwatersinourbodywillbelost,theplasmaisconcentrated,sotheRBCnumbersisrelativelyincreasing.Somediseases,suchasheartdisease,lungdisease,canalsocausethenumberofRB