揉髌手法对兔膝关节骨关节病模型血常规影响的研究_戴七一

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1、·1564·辽宁中医杂志2015年第42卷第8期DOI∶10．13192/j．issn．1000-1719．2015．08．074揉髌手法对兔膝关节骨关节病模型血常规影响的研究121121111111戴七一，黎强，阮萍，覃学流，刘靖，滕居赞，容向宾，韩杰，覃杰，康持，徐通，陈一鑫(1．广西中医药大学附属瑞康医院，广西南宁530011;2．广西中医药大学，广西南宁530001)摘要:目的:观察揉髌手法对兔膝关节骨关节病模型血常规的影响，进而探讨其治疗的可能作用机制。方法:60只新西兰兔分为手法组、模型组、假模组和正常组各15只。前两组通过手术造成骨内高压型动物模型。造模1周后手法

2、组手法施术5周共17次。造模后12周末分别处置动物，取血检测血常规;膝关节软骨组织评判退变程度，数据经统计学处理。结果:模型组软骨组织退变明显，与手法组比较差异有统计学意义;手法组、模型组、假模组和正常组动物血常规各项指标比较差异无统计学意义。结论:揉髌手法对兔膝关节骨关节病模型血常规的变化无明显影响。关键词:按摩;骨关节病;动物模型;血常规;实验研究中图分类号:Ｒ684文献标志码:A文章编号:1000-1719(2015)08-1564-03EffectofKneadingPatellaManipulationonBloodＲoutineTestofＲabbitKneeOst

3、eoarthritisModel12112111DAIQiyi，LIQiang，ＲUANPing，QINXueliu，LIUJing，TENGJuzan，ＲONGXiangbin，HANJie，1111QINJie，KANGChi，XUTong，CHENYixin(1．TheAffiliatedＲuikangHospitalofGuangxiUniversityofTraditionalChineseMedicine，Nanning530011，Guangxi，China;2．GuangxiUniversityofTraditionalChineseMedicine，Nanni

4、ng530001，Guangxi，China)Abstract:Objective:Toobservetheeffectofkneadingpatellamanipulationonthebloodroutinetestofrabbitkneeosteoar-thritismodelanddiscussthepossiblemechanismactionofthetreatment．Methods:60NewZealandrabbitswererandomlydividedintofourgroups:manipulationgroup，modelgroup，dummy－mod

5、elgroupandthenormalgroup，15rabbitsineachgroup．Ahighintraosseouspressuremodelwasestablishedinthemanipulationgroupandmodelgroup．Aweekaftermodeling，kneadingpatellamanipulationwasperformed17timesforeachrabbitinthemanipulationgroupin5weeks．12weeksaftermodeling，wedisposedtheanimals，takingthebloods

6、amplingforroutinetestingandthekneejointcartilagetissuefordetectionofdegenerationandthedataforstatisticalprocessing．Ｒesults:Thecartilagedegenerationinaseriousformodelgrouphadsignificantdifferencecomparedwiththatofthemanipulationgroup．Therewasnosignificancedifferenceforbloodroutinetestresultam

7、ongallthegroups．Conclu-sion:Thereisnoobviouseffectofkneadingpatellamanipulationonthebloodroutinetestofrabbitkneeosteoarthritismodel．Keywords:manipulation;kneeosteoarthritis;animalmodel;bloodroutinetest;study揉髌手法是由捏拿股四头肌、先顺时针后逆时针1.2实验仪器旋转揉按患膝髌骨和屈伸牵张