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1、地佐辛应用与临床全麻苏醒的疗效分析摘要:目的:分析地佐辛在全麻苏醒患者的应用中的临床效果。方法:取本院外科于2008年4月至2011年4月收治的118例进行全麻手术治疗的患者,随机分为观察组和对照组各59例。对照组59例患者使用丙泊酚2.2mg/kg,瑞芬太尼4.3ug/kg进行全麻诱导,术中间断性吸入七氟烷(1%-3%)维持血流动力学的稳定,于手术结束前15min停止七氟烷的吸入,前5min停止丙泊酚与芬太尼的注射,等待患者苏醒,观察组59例患者除使用与对照组一样的麻醉方式、用药之外,在全麻苏醒期加用地佐辛。比较两组在
2、全麻苏醒期各项指标及不良反应发生率等的差异。结果:观察组的各项指标均优于对照组,两组比较有统计学差异,P<0.05;观察组的不良反应发生率明显低于对照组,两者比较有统计学差异,P<0.05。结论:地佐辛可缩短手术治疗患者的全麻苏醒时间和拔管时间等,减少不良反应的发生,有助于提高麻醉安全性,值得在临床麻醉中广泛推广使用。关键词:地佐辛全麻苏醒DezocineapplicationandclinicalanalysisoftheeffectofrecoveryfromgeneralanesthesiaAbstract:Obj
3、ective:toanalyzedezocineinanesthesiarecoveryinpatientswiththeclinicaleffectoftheapplication.Methods:thehospitalin2008Aprilto2011April,118casesofgeneralanesthesiaoperationtreatedpatients,wererandomlydividedintotheobservationgroupandthecontrolgroupwith59casesineach
4、group.Acontrolgroupof59patientsusingpropofolremifentanilin2.2mg/kg,4.3ug/kgduringinductionofgeneralanesthesia,postoperativeintermittentinhalationsevenhalothane(1%-3%)maintainhemodynamicstability,inoperationbeforetheendofseven15minstophalothaneinhalation,former5mi
5、ndiscontinuationofpropofolandfentanylinjection,waitingforthepatientregainsconsciousness,theobservationgroup59casesandcontrolgroupexceptforuseasanaesthesiaway,outsidethedrug,intherecoveryperiodofgeneralanesthesiacombinedwithdezocine.Comparisonofthetwogroupsinthere
6、coveryperiodofgeneralanesthesiaindicatorsandtheincidenceofadversereactionsandotherdifferences.Results:theobservationgroupindicatorsarebetterthanthecontrolgroup,twogroupshadsignificantdifference,P<0.05;theincidenceofadversereactionsinobservationgroupwassignificant
7、lylowerthanthecontrolgroup,thereissignificantdifferencebetweenthetwo,P<0.05.Conclusion:withXinKeshorteningoperationfortreatmentofpatientswithgeneralanesthesiatimeofawakeningandextubationtime,reducetheoccurrenceofadversereactions,contributetoimprovinganestheticsaf
8、ety,iswidelyusedinclinicalanesthesia.Keywords:Dezocinewakeupofgeneralanesthesia目前由于各类疾病的多发,手术治疗成为一种主要的有效治疗的方式,随着外科技术的发展,麻醉学科也随之飞速前进,目前临床较大手术多使用全身麻醉,力求患者在安全舒适的条