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3、GP73联合AFP对PHC的早@@[12]Jin-songHu,De-wuWu,ShuoLiang,etal.GP73,aresident期诊断价值探讨[J].放射免疫学杂志，2010，23:205-206.Golgiglycoprotein,issensibilityandspecificityforhepatocel2010-01-19自身免疫性胰腺炎临床研究进展辛磊高阳李兆申[提要]近年来，自身免疫性胰腺炎(AIP)研究逐渐进展。AIP是由自身免疫机制介导的，以淋巴细胞、浆细胞浸润伴有胰腺纤维化及功能障碍为特征的特殊的慢
4、性胰腺炎，可累及胆管、涎腺、肾等胰外器官。常见的临床表现包括梗阻性黄疸、腹痛、体重减轻等，类似于胰腺癌。本病采用类固醇类药物治疗效果显著。目前，各国的AIP诊断标准尚未达成一致。对其病理学分型、影像学表现、血清学标志、活检技术均有各种新进展，而AIP与胰腺癌的鉴别诊断则是研究热点。自身免疫性胰腺炎；诊断标准；鉴别诊断AdvancesinclinicalresearchonautoimmunepancreatitisXINLeiGAOYangLIZhao-shenDepartmentofGastroenterology,Shan
5、ghaiChanghaiHospital,SecondMilitaryMedicalUniversity,200433,Shanghai,P.R.China[Abstract]Inrecentyears,researchonautoimmunepancreatitis(AIP)hasgainedsignificantprogress.AIPisaspecialtypeofchronicpancreatitiswhichismediatedbyanautoimmunemechanism.Itischaracterizedbyth
6、einfiltrationoflymphocytesandplasmacellsleadingtopancreaticfibrosisanddysfunction.AIPcanaffectthebileducts,salivaryglands,kidneysandotherorgansoutsidethepancreas.Thecommonmanifestationsincludeobstructivejaundice,abdominalpain,andweightloss,whicharesimilartopancreati
7、ccancer.Steroidtherapyisofsignificanteffect.ThereisnoconsensusnowadaysonthediagnosticcriteriaofAIPacrosstheworld.Therearemanystudiesonthepathologicalsubtypes,imaging,serologicalmarkersandbiopsytechniquesonAIP,andresearchfocusesonthedifferentialdiagnosisfrompancreati
8、ccancer.[Keywords]Autoimmunepancreatitis;Diagnosticcriteria;Differentialdiagnosis10.3760/cma.j.issn.1007-8118.2011.12.02200433上海，第二军医大学附属长
