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时间:2019-06-01
《小口径人工血管血液相容性》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据中国组织工程研究与临床康复第J2眷第6期2008—02—05出版JournalofClinicalRehabilitativeTissueEngineeringResearchFebruary只2008V01.12.No.6小口径人工血管血液相容性☆欧阳晨曦1,李沁1,王维慈1,周飞2,徐卫林2,李文斌2Bloodcompatibilityofsmall-calibervasculargraftsOuyangChen-xil,LiQinl.WangWei·cil,ZhouFei2,XuWei—lin2,LiWen-bin2AbstractBACKGROUND:Atpresent,ab
2、reakthroughstudyhasbeenachievedforthebig—calibervasculargrafts.whichhavebeenwidelyappliedintheelinicalpractice.WhiJetherearcstillsomeunsolvedkeyproblemsinfieldoftIlesmall.caliber(1essthan6llnndiameter)vasculargrafts,suchasvascularembolismandhistocompatibility.whichobstructsthepracticaluseofsmall.ca
3、libervasculargrafts.OBJECTIVE:Tointroducethecurrentstudyofvasculargrafts,analyzetheproblemsofdesigningsmall-calibervasculargrafts,andexplainthemethodofenhancingbloodcompatibility.RETRIEVALSTRATEGY:Acomputer-basedsearchwasundertakeninWWW.cnki.netandMedline(www.pubmed.com)toidentifytheatticlesaboutth
4、ebloodcompatibilltyofsmall-calibervasculargraftbetweenJanuary1975andAugnst2007.witIlthekeywordsof”Vasculargrafts,Polyurethane,Bloodcompatibility”inChineseandEnglish.Aftertheprimarycheck,atotalof143articleswerecollected.including28Chineseonesand1l5Englishones.LITERATUREEVALUATIoN:Thetitlesandabstrac
5、tsweresoreenedpreliminarily.thentherewere54articlesexcludedduetounrelatedobjectivesand64atticlesdeletedduetorepeatedcontents.finally25literatureswereinvolvedintheanalysis,including13onesregardinganimalexperiments,andinvivo,exvivo,cytologicaltrials,12onesregardingreviews,commentariesandlectures.DATA
6、SYNTHESIS:O)Thematerialsforbloodvesselprosthesisalemaialydacron,polyteflnaturalsilkandsoon,whilepolyurethanewithgoodcompliance,abradability,elasticity.biocompatibilityandanfcoagulantproperty,hasgmnedmuchattraction.②Small.calibervasculargraftsaleabsentsintheantithromboticeffect,andmayresultinvascula
7、rocclusionofgraftsthroughmuralthrombosisoccurredinlumenofbloodvessel,whichinducesthebloodcoagulationhyperfunction.slowsthebloodflow,andthickensthrombuslayer.③Asforthebloodcompatibility,山erearemanystudiesabo
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