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1、中国组织工程研究与临床康复雳12着第1声2008一01一01出版JournalofClinicalRehabilitativeTissueEngineeringResearchJanuaryl,2008Vol.12,No.lVCR绘Jy高分子材料小口径人造血管的相关研究★王维慈‘，欧阳晨曦‘，周飞2，徐卫林2，金毕，，李毅清‘扮...口..........................................................口口.............曰......................日............................
2、..................Polymermaterialsassmall-calibervasculargraftsWangWe!-d1,OuyangChen-xit,ZhouFei2,XuWei-line,JinBit,LiYi-gingrAbstract︸一UBACKGROUND:Atpresent,abreakthroughstudyhasbeenachievedforthebig-calibervasculargrafts,whicharewidelyappliedintheclinicalpractice.Whiletherearestillsomeunsolv
3、edkeyproblemsofsmall-calibervasculargrafts,suchasvascularTCUembolismandhistocompatibility,whichobstructsthepracticaluseofsmall-calibervasculargraftsOBJECTIVE:Tocomparethebiocompatibilityandcomplianceofseveralvasculargrafts,andprobethebestmaterialforsmall-diametervasculargrafts.HW一RETRIEVALSTRA
4、TEGY:Acomputer-basedsearchwasundertakeniswww.cnki.netandMedline(www.pubmed.com)toidentifythearticlesaboutthebiocompatibilityofvasculargraft,aswellascomplianceofsmall-diametervasculargraftsbetween︸一TJanuary1985andAugust2007,withthekeywordsof"Vasculargrafts,Polyurethane,Biocompatibility"inChines
5、eandEnglish.Aftertheprimarycheck,atotalof138articleswerecollected,including32Chineseonesand106Englishones.AUaLITERATUREEVALUATION:Therewere42articlesexcludedduetounrelatedobjectivesand67articlesduetorepeatedcontents,finally29literatureswereinvolvedintheanalysis,including20onesregardinganimalex
6、periments,andin~，exvivo,cytologicaltrials,9onesregardingreviews,commentariesandlectures.W一、DATASYNTHESIS:Theidealsmall-diametervasculargraftsrequiregoodphysicalstability,mechanicalproperty,biocompatibility,anticoagulantpropertyandinfectivityresistance.Amongthem,mechanicalpropertyandbiocompatib
7、ilityhaveacrucialroleinensuringthelong-termstabilityandpatencyofvesse玩aswellasadvancevasculargrafttechnique.Polyurethaneispreferredowingtoitsbiocompatibility;whiletheundegradablepolyurethaneandexpandedpolytetrafluoroethylenearefavorable
