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1、NEURALREGENERATIONRESEARCHVolume7,Issue5,February2012www.nrronline.orgCitethisarticleas:NeuralRegenRes.2012;7(5):352-358.Long-termanodalblockstimulationatsacralanteriorrootspromotedrecoveryofneurogenicbladderfunctioninarabbitmodelofcompletespinalcordi
2、njury☆1221132XiaoranWang,QiGao,XiaoyuYang,WeihuaWang,XinquanGu,GuifengLiu,PengYan,4556711GeGao,XinYu,YongjieWang,JihuLian,ChaolingShi,YaoWang,LiFan1DepartmentofUrology,China-JapanUnionHospitalofJilinUniversity,Changchun130033,JilinProvince,China2Depar
3、tmentofOrthopedics,China-JapanUnionHospitalofJilinUniversity,Changchun130033,JilinProvince,China3DepartmentofRadiology,China-JapanUnionHospitalofJilinUniversity,Changchun130033,JilinProvince,China4DepartmentofPathology,China-JapanUnionHospitalofJilinU
4、niversity,Changchun130033,JilinProvince,China5DepartmentofCriticalCareMedicine,People’sHospitalofJilinProvince,Changchun130021,JilinProvince,China6DepartmentofUrology,JilinProvincialHospital,Changchun130021,JilinProvince,China7DepartmentofUrology,theF
5、ourthHospitalofJilinUniversity,Changchun130011,JilinProvince,ChinaAbstractAcompletespinalcordinjurymodelwasestablishedinexperimentalrabbitsusingthespinalcordXiaoranWang☆,Studyingfordoctorate,Departmentofclipcompressionmethod.Urodynamicexaminationwaspe
6、rformed2weekslatertodetermineUrology,China-JapanUnionneurogenicbladderstatus.TherabbitsweretreatedwithanodalblockstimulationatsacralHospitalofJilinUniversity,anteriorrootsfor4weeks.ElectricalstimulationofsacralanteriorrootsimprovedurodynamicChangchun1
7、30033,JilinProvince,Chinaparametersofneurogenicbladderinrabbitmodelsofcompletespinalcordinjury,effectivelypromotedurinaryfunction,andrelievedurinaryretention.ImmunohistochemistryresultsshowedXiaoranWangandQiGaocontributedequallytothisthatabalancewasac
8、hievedamongexpressionofmuscarinicreceptorsubunitsM2,M3,work.ATP-gatedionchannelP2X3receptors,andβ2-adrenergicreceptor,andnervegrowthfactorexpressiondecreased.Theseresultssuggestedthatlong-termsacralanteriorrootstimulationofCorrespondingauthor:
