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时间:2019-05-21
《化痰祛瘀方加减联合硫唑嘌呤片治疗白塞病27例临床观察》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、494河北中医2015年4月第37卷第4期HebeiJTCM,April2015,Vol37,No.4论著doi:10.3969/j.issn.1002-2619.2015.04.005化痰祛瘀方加减联合硫唑嘌呤片治疗※白塞病27例临床观察1234谷占卿王勇郝静敏曹玉兰郑晓春杨晓庆(河北省邯郸市中医院风湿病科,河北邯郸056001)【摘要】目的观察化痰祛瘀方加减联合硫唑嘌呤片治疗白塞病的临床疗效。方法将50例白塞病患者随机分为2组。治疗组27例予化痰祛瘀方加减联合硫唑嘌呤片治疗,对照组23例予硫唑嘌呤片治疗,2组均治疗2个月。比较2组临床疗效及治疗前后C反应蛋白
2、(CRP)、免疫球蛋白(Ig)A变化。结果2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。2组治疗后CRP及IgA均较本组治疗前降低(P<0.01),且治疗组降低更明显(P<0.05)。结论化痰祛瘀方加减联合硫唑嘌呤片治疗白塞病疗效显著,可提高免疫力。【关键词】贝赫切特综合征;中西医结合疗法【中图分类号】R593.2;R751.0;R2-031【文献标识码】A【文章编号】1002-2619(2015)04-0494-03ClinicalobservationofChineseherbsfordissipatingphlegmandremo
3、vingbloodstasiscombinedwithaza-**thioprinetabletsonbehcet'sdiseaseGUZhanqing,WANGYong,HAOJingmin,etal.DepartmentofRheuma-tism,HandanCityHospitalofTraditionalChineseMedicineinHebeiProvince,Hebei,Handan056001【Abstract】ObjectiveToobservetheclinicaleffectsofChineseherbsfordissipatingphle
4、gmandremovingbloodstasiscombinedwithazathioprinetabletsonbehcet'sdisease.Methods50patientswithbehcet'sdiseasewererandomlydividedintotwogroups.27patientsintreatmentgroupreceivedChineseherbsfordissipatingphlegmandre-movingbloodstasiscombinedwithazathioprinetablets,23patientsincontrolgr
5、oupreceivedazathioprinetablets.Thecoursewastwomonthsintwogroups.Theclinicaleffectsthechangesofc-reactiveproteinandimmunoglobulinIgAwerecomparedbeforeandaftertreatmentintwogroups.ResultsTherewasstatisticalsignificancebetweentwogroupsonthetotaleffectiverate(P<0.05),thecurativeeffectint
6、reatmentgroupwasobviouslybetterthanthatincontrolgroup.CRPandIgAaftertreatmentweredecreasedintwogroups(P<0.01),andthedecreaseintreatmentgroupwasmoredistinctcomparedwiththatincontrolgroup(P<0.05).ConclusionChineseherbsfordissipatingphlegmandremovingbloodstasiscombinedwithazathioprineta
7、bletsonbehcet'sdiseasehassignificantclinicaleffect,improveimmunity.【Keywords】Behcet'ssyndrome;CombinedtherapyofChineseandwesternmedicines白塞病又称贝赫切特综合征,是一种以口腔、可受累,10%的患者出现大中血管炎,即指任何部外阴溃疡、眼部虹膜炎及皮肤损害为临床特征的位的大中动脉炎和大中静脉炎,当动脉及其分支累及多个系统的慢性疾病。本病全身大小血管均血管壁发生炎症时,可使管壁增厚,继而血栓形成使管腔变窄,同时可使动脉壁的弹力纤维遭
8、到破※项目来源:河北省中
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