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1、·110·中国微创外科杂志2010年2月第10卷第2期ChinJMinInvSurg,February2010,Vol.10.No.2·临床论著·支气管内超声引导针吸活检术(EBUS2TBNA)临床应用的初步体会3赵辉王俊李剑锋李运周足力卜梁(北京大学人民医院胸外科,北京100044)【摘要】目的探讨支气管内超声引导针吸活检术(endobronchialultrasound2guidedtransbronchialneedleaspiration,EBUS2TBNA)在明确纵隔和肺门肿大淋巴结定性诊断中的应用价值。方法2009年9～11月,对
2、25例胸部CT检查提示纵隔和(或)肺门淋巴结肿大(短径>1cm)进行EBUS2TBNA检查,阴性者进一步接受纵隔镜检查或胸腔镜、开胸手术加以确证。结果本组25例共穿刺32组淋巴结。EBUS2TBNA明确淋巴结恶性转移者15例;EBUS2TBNA阴性者10例,其中1例开胸术后证实隆突下淋巴结转移。EBUS2TBNA在纵隔和肺门肿大淋巴结良恶性鉴别诊断中的敏感性、特异性和准确性分别为94%(15/16),100%(9/9)和96%(24/25)。所有患者检查耐受良好,无任何相关并发症发生。结论EBUS2TBNA是评价纵隔及肺门淋巴结安全有效的方法
3、。【关键词】支气管内超声;经支气管针吸活检;淋巴结;诊断中图分类号:R655.304文献标识:A文章编号:1009-6604(2010)02-0110-04PreliminaryExperienceonEndobronchialUltrasound2GuidedTransbronchialNeedleAspiration(EBUS2TBNA)ZhaoHui,WangJun,LiJianfeng,etal.DepartmentofThoracicSurgery,RenminHospital,PekingUniversity,Beijing100
4、044,China【Abstract】ObjectiveToassesstheefficacyofendobronchialultrasound2guidedtransbronchialneedleaspiration(EBUS2TBNA)inthediagnosisofenlargedmediastinalandhilarlymphnodes.MethodsFromSeptember2009toNovember2009,25patientswithmediastinaland/orhilarlymphadenopathy(minimumdi
5、ameter>1cm)detectedonchestCTscanwereincludedinthestudy.AllpatientswithnegativeEBUS2TBNAsubsequentlyunderwentmediastinoscopy,thoracoscopy,oropenthoracotomyasaconfirmatorytest.ResultsInthe25patients,EBUS2TBNAwasperformedtoobtainsamplesfrom32groupsoflymphnodes.EBUS2TBNAreveale
6、dmetastaticlymphnodesinvolvementin15patients.TenpatientsshowednegativeEBUS2TBNA,nineofthemwereconformedbysurgicalbiopsy,andmetastaticnodewasdiagnosedinoneofthenine.Thesensitivity,specificity,andaccuracyofEBUS2TBNAindistinguishingbenignfrommalignantlymphnodeswere94%(15/16),1
7、00%(9/9),and96%(24/25),respectively.Theprocedurewasuneventful,andtherewerenocomplications.ConclusionEBUS2TBNAisasafeandeffectivemethodforevaluatingmediastinalandhilarlymphnodes.【KeyWords】Endobronchialultrasound;Transbronchialneedleaspiration;Lymphnodes;Diagnosis支气管内超声引导针吸活检
8、术(endobronchialTBNA检查,临床效果满意,现报道如下。ultrasound2guidedtransbronchialneedleaspiration
