放松训练对造血干细胞移植患者回输后至植活前焦虑的影响

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1、授予单位代码10089学号或申请号13866HebeiMedicalUniversity硕士学位论文科学学位放松训练对造血干细胞移植患者回输后至植活前焦虑的影响作者姓名：史楠导师：何文英主任护师专业：护理学二级学院：河北医科大学第二医院2015年03月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有r河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河

2、北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。研究生签名：导师签章二级学院领导盖章：T3…年b月丨日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：导师签章：例戏2叫，年G月（日目录中文摘要·············································

3、································1英文摘要·············································································3研究论文放松训练对造血干细胞移植患者回输后至植活前焦虑的影响前言·············································································6材料与方法·····························

4、·······································6结果·············································································10附表·············································································13讨论·······················································

5、······················16结论·············································································20参考文献·······································································26附录···········································································

6、··28综述造血干细胞移植患者心理应激及干预策略的研究进展·············22致谢···················································································31个人简历·············································································32中文摘要放松训练对造血干细胞移植患者回输后至植活前焦虑的影响摘要目的：造血干细胞移植是指经

7、静脉向患者输入具有造血潜能的健康干细胞,重新建立造血功能,从而达到治疗疾病的目的。随着造血干细胞移植技术的发展，该疗法已成为目前治疗白血病、遗传性疾病、恶性实体瘤等疾病的主要方法。在移植过程中，由于患者处于封闭的治疗环境，加上超大剂量的放射治疗与化疗药物、免疫抑制剂等所导致的不良反应及副作用，以及治疗过程中各种并发症所造成的痛苦等均可导致患者在造血干细胞移植期间产生明显的负性情绪，从而影响疾病的治疗和恢复。造血干细胞移植患者一般经历反应期、假愈期、极期、恢复期四个阶段。四阶段中的极期是指回输后至植活前期间（+2天

8、—+9天），患者白细胞接近零值，对于是否能够成功植活充满不确定性，最容易出现焦虑的负性心理问题。因此，运用放松训练来减轻或消除造血干细胞移植患者的焦虑情绪，增加移植患者的治疗依从性，提高移植的成功率受到越来越多的临床心理工作人员和移植医务工作人员的重视与关注。本研究目的在评价放松训练对造血干细胞移植患者极期焦虑水平、心率及收缩压的影响。方法：本研究为实验性研究。选取201