mgonf-kb炎症信号通路在糖尿病痛性神经病变中的作用

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1、分类号：R587.1学校代码：10114密级：学号：2012200529MGO/NF-kB/炎症信号通路在糖尿病痛性神经病变中的作用TheRoleofMGO/NF-kB/InflammatorySignalingPathwaysinPainfulDiabeticNeuropathy研究生：张雪利指导教师：李全民教授专业名称：内科学研究方向：内分泌与代谢病学位类型：专业学位所在学院：第二临床医学院中国山西二〇一五年五月十五日目录中文摘要······································································

2、·········································I英文摘要············································································································VI常用缩写词中英文对照表·····················································································X前言··································

3、················································································11实验材料与方法·······························································································31.1研究对象及分组·························································································31.2主

4、要仪器及设备·························································································51.3研究方法·································································································101.4主要观察指标的测定方法·········································································

5、111.5统计学处理······························································································162结果··········································································································172.1四组基线资料及生化指标相比较·······················································

6、········172.2血清MGO的变化····················································································182.3TNF-α的基因表达与血清NF-kB的变化···················································192.4相关性分析······························································································213

7、讨论··········································································································264结论··········································································································30参考文献·········································