高糖诱导肾小管上皮细胞自噬激活以及glp-1类似物利拉鲁肽对其调节作用的研究

《高糖诱导肾小管上皮细胞自噬激活以及glp-1类似物利拉鲁肽对其调节作用的研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、分类号R587.2第四军医大学UDC616.4TheFourthMilitaryMedicalUniversity密级公开博士学位论文高糖诱导肾小管上皮细胞自噬激活以及GLP-1类似物利拉鲁肽对其调节作用的研究赵昕培养类别全日制学位类型学术学位一级学科(专业类)临床医学二级学科(专业)内科学（内分泌与代谢病）研究方向糖尿病并发症的机制指导教师姬秋和教授（主任医师）培养单位第四军医大学西京医院内分泌科二O一五年五月第四军医大学博士学位论文目录缩略语表············································

2、················································································1中文摘要····························································································································3英文摘要························································

3、····································································7前言··························································································································11文献回顾一······································································

4、················································13文献回顾二······················································································································17文献回顾三··························································································

5、····························25正文··························································································································27第一部分高糖对人近端肾小管上皮细胞的损伤作用············································271材料···········································

6、············································································272方法·······················································································································283结果·································································

7、······················································334讨论·······················································································································37第二部分高糖诱导人肾小管上皮细胞自噬激活以及利拉鲁肽对其调节作用·····391材料················································

8、·······································································392方法··································