丙泊酚与依托咪酯全凭静脉麻醉对妇科腹腔镜手术患者脑血流量和颅内压影响的比较

丙泊酚与依托咪酯全凭静脉麻醉对妇科腹腔镜手术患者脑血流量和颅内压影响的比较

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丙泊酚与依托咪酯全凭静脉麻醉对妇科腹腔镜手术患者脑血流量和颅内压影响的比较_第1页
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1、授予单位代码10089学号或申请号13434#/Ml‘办乡HebeiMedicalUniversity在职科学学位丙泊酚与依托咪酯全凭静脉麻醉对妇科腹腔镜手术患者脑血流量和颅内压影响的比较学位申请人:姚长青导师:康荣田教授专业:麻醉学二级学院:第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下,由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署

2、名为单位河北医科大学,试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则,承担相应法律责任。研究生签名导师签章:二级学院领导盖章:年:r月o日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。本论文由本人独立撰写,文责自负。研究生签名:^

3、•签章:mCT年r月0日目录中文摘要·············································

4、································1英文摘要·············································································2英文缩写·············································································3研究论文丙泊酚与依托咪酯全凭静脉麻醉对妇科腹腔镜手术患者脑血流量和颅内压影响的比较前言·····················

5、························································4材料与方法····································································6结果·············································································9附表················································

6、·····························10讨论·············································································12结论·············································································18参考文献································································

7、·······19综述颅内压和脑血流量增高的机制及影响因素··························21致谢···················································································29个人简历·············································································31中文摘要丙泊酚与依托咪酯全凭静脉麻醉对妇科腹腔镜手术患者脑血流量和颅

8、内压影响的比较摘要目的:通过比较丙泊酚与依托咪酯乳剂分别复合瑞芬太尼的全凭静脉麻醉下,妇科腹腔镜手术患者的脑血流量和颅内压的变化,评价二者对妇科腹腔镜手术患者的脑血流量和颅内压的影响,为此类患者的临床麻醉方法的选择提供参考。方法:选择衡水市哈励逊国际和平医院择期行妇科腹腔镜手术患者40例(ASA分级为Ⅰ~Ⅱ级),随机分成两组。I组:以咪达唑仑-芬太尼-依托咪酯乳剂-苯磺酸顺阿曲库铵诱导麻醉,麻醉维持使用依托咪酯乳剂复合瑞芬太尼;II组:以咪达唑仑-芬太尼-丙泊酚-苯磺酸顺阿曲库铵诱导麻醉,麻醉维持使用丙泊酚复合瑞芬太

9、尼。分别于麻醉前平卧位稳定后5min(T1),气管插管后即刻(T2),气管插管后5min(T3),气腹头低位即刻(T4),气腹头低位后15min(T5)和恢复平卧位无气腹后5min(T6)时,使用经颅多普勒超声仪测定患者大脑中动脉收缩期峰值流速和搏动指数。结果:1与II组比较,I组在T3、T4、T5时刻的大脑中动脉收缩期峰值流速和搏动指数高,差

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