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时间:2020-05-02
《依托咪酯乳剂与丙泊酚全凭静脉麻醉在妇科腹腔镜手术中的应用比较.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、依托咪酯乳剂与丙泊酚全凭静脉麻醉在妇科腹腔镜手术中的应用比较李妮娟,唐勇(成都市锦江区妇产科医院麻醉科,成都610016)中图分类号R713文献标志码A文章编号1001.0408(2013)20.1865.03DOI10.6039~.issn.1001-0408.2013.20.15摘要目的:比较依托咪酯乳剂与丙泊酚联合瑞芬太尼全凭静脉麻醉对妇科腹腔镜手术患者血流动力学的影响与安全性。方法:将择期行妇科腹腔镜手术患者6O例随机均分为依托咪酯组(E组)与丙泊酚组(P组)。分别应用依托咪酯乳剂或丙泊酚联合瑞芬太尼全凭静脉麻醉。观察两组患者围麻醉期各时间点血流动力学的变化及停药后患者各阶
2、段恢复时间,以及用药后患者反应、术后24h内不良反应发生情况。结果:诱导时,P组收缩压(SBP)、舒张压(DBP)和心率(HR)与麻醉前比较显著下降(尸<0.05),而E组则轻度下降或下降不显著(P>O.05);气管插管时及插管后1min,P组SBP与DBP显著高于诱导前(P<0.05),而E组轻度升高(P>0.05),插管后3~5min和手术开始时,P组SBP与DBP也显著升高,而E组SBP与DBP低于P组(尸<0.05)。在整个围麻醉期间,E组血压及HR与P组比较波动较小,而两组患者自主呼吸恢复、睁眼、拔除气管导管及清醒时间比较无显著性差异(P>0.05)。两组患者均未见严重不
3、良反应发生。结论:依托咪酯乳剂全凭静脉麻醉时血流动力学比丙泊酚更加稳定,对循环功能干扰轻,更适合用于时间短、恢复快的妇科腹腔镜手术麻醉。关键词依托咪酯乳剂;丙泊酚;瑞芬太尼;妇科腹腔镜手术;全凭静脉麻醉ComparisonofIntravenousAnesthesiaofEtomidateEmulsionorPropofolinGynecologicalLaparoscopicOperationLINi-juan,TANGYong(Dept.ofAnesthesiology,ChengduJinjiangDistrictObstericsandGynecologyHospi—tal
4、,Chengdu610016,China)ABSTRACTOBJECTIVE:Tocomparetheefects,clinicaleficacyandsafetyoftotalintravenousanesthesiaofEtomidateemul—sionorpropofolcombinedwithremifentanilonhemodynamicsofpatientsunderwentgynecologicallaparoscopicoperation.METH—ODS:60patientsundergoingelectivegynecologicallaparoscopic
5、operationwererandomizedintoetomidategroup(groupE)andpropofolgroup(groupP).Thehemodynamicchangesofpatientsin2groupswereobservedatdiferenttimepointsofstageofalleN—thesia,andrecoverytimewasalosobservedafterdrugwithdrawa1.TheresponseofpatientsaftertheinjectionandtheoccurrenceofADRwithin24hafterope
6、rationwereobserved.RESULTS:Duringinduction,SBP,DBPandHRofgroupPdecreasedobvious·ly,comparedwithbeforeanesthesia(P<0.o5);thoseofgroupEdeclinedslightlyorhadnoevidentdecrease(P>0.05).SBPandDBPofgroupPduringtrachealintubationand1minafterintubationweresignificantlyhigherthanbeforeinduction(P<0.05),
7、andthoseofgroupEincreasedslightly(P>0.05).SBPandDBPofgroupPincreasedsignificantly3-5minutesafterintubationandatthebeginningofoperation,andthoseofgroupEwerelowerthangroupP(P<0.05).PerianestheticbloodpressureandheartrateofgroupEhadnosigni
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