解郁安眠方治疗抑郁、焦虑共病的临床研究

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1、ShanxiUniversityofChineseMedicineJieyuanmianDecoctionintheTreatmentofDepressionandAnxietyClinicalResearch~Vfli~i.g,Il.R.flF=~1faJe~~tJtm~*ll-'~!ll!_~~:r:p~~*4~~~~:~~~~~••m~=o-1i:fF/,.F.J_B中文摘要目的通过对比解郁安眠方和舒肝解郁胶囊二者对于抑郁、焦虑共病治疗前后的汉密尔顿抑郁量表（HAMD）和汉密尔顿焦虑量表（HAMA）评分的减分数

2、以及临床总体疗效，来评价解郁安眠方治疗抑郁、焦虑共病的临床效果，为临床应用提供客观依据，并为进一步的研究奠定基础。方法对符合纳入标准的患者纳入观察范围，使用汉密尔顿抑郁量表（HAMD）和汉密尔顿焦虑量表（HAMA）进行治疗前评分，经用解郁安眠方和舒肝解郁胶囊治疗28天之后，再用汉密尔顿抑郁量表（HAMA）和汉密尔顿焦虑量表（HAMA）分别进行治疗后评分。期间釆用治疗前后自身对照与组间对照研究方法，观察评分状况及疗效情况。全部数据均采用SPSS17.0统计软件进行统计分析。结果疗程结束后，在试验组和对照组的汉密尔顿抑郁

3、量表(HAMD)和汉密尔顿焦虑量表(HAMA)对比中，试验组解郁安眠方明显优于对照组舒肝解郁胶囊的疗效，且解郁安眠方的副反应小于舒肝解郁胶囊。可以肯定解郁安眠方的临床疗效和安全性。结论解郁安眠方对于治疗少阳枢机不利的抑郁、焦虑共病有着较强的针对性，其临床症状改善情况较好且副反应较小。而且解郁安眠方在治疗抑郁和焦虑共病中对于焦虑症的改善情况较为突出。关键词：解郁安眠方；抑郁；焦虑；临床研究IAbstractObjective：ContrasttoJieyuanmiandecoctionandJieyuanmiancap

4、sulefordepressionandanxiety,bothbeforeandafterthedecreasescoresofHAMD,HAMAscoresandclinicalcurativeeffect.AndobserveJieyuanmiandecoctionontheimprovementoftheTCMsymptomsofdepressionandanxiety,provideobjectivebasisforclinicalapplicationandlaythefoundationforfurth

5、erstudy.Methods：Thepatientsinaccordancewitheligibilitycriteriaintotheobservationrange,usingtheHamiltondepressionratingscaleandHamiltonanxietyscalescoresbeforetreatment,aftertreatmentwithJieyuanmiandecoctionandShuganjieyucapsuleafter28days,withHamiltondepression

6、ratingscaleandHamiltonanxietyscalescoresaftertreatmentrespectively.Duringthecalculationbeforeandaftertreatmentbetweenself-reflectionandgroupcontrolstudymethod,theobservedscoreconditionandcurativeeffect.AllthedatausingSPSS17.0statisticalsoftwareforstatisticalana

7、lysis.Results：Afterthetreatment,contrasttotheexperimentalgroupandcontrolgroupofHamiltondepressionratingscale(HAMD)andHamiltonanxietyscale(HAMA),theexperimentalgroupJieyuanmiandecoctionisbetterthanthecontrolgroupShuganjieyucapsuleofcurativeeffect,itseffectivenes

8、sisalsohigherthanthecontrolgroup,andthesideeffectofJieyuanmiandecoctionislessthanShuganjieyucapsule.CertainlyJieyuanmiandecoctionoftheclinicalefficacyandsafety.Conclusion：Ji