溶血性曼氏杆菌A1、A2血清型标准株的灭活疫苗制备和免疫效果评价

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1、分类号：密级:HUAZHONGAGRICULTURALUNIVERSITY硕士学位论文MASTER’SDEGREEDISSERTATION溶血性曼氏杆菌A1、A2血清型标准株的灭活疫苗制备和免疫效果评价THEPREPARATIONANDIMMUNEEFFICACYEVALUATIONOFTYPEA1、A2M.HAEMOLYTICAVACCINE研究生:胥耀文CANDIDATEXUYAOWEN学号:2016302120049STUDENTNO.专业:兽医硕士MAJOR:CLINICALVETERINARYMEDICINE导师:陈建国副教授SUPERVISOR:ASSOCIA

2、TEPROFESSORCHENJIANGUO中国武汉WUHAN，CHINA二○一八年六月JUNE，2018华中农业大学硕士学位论文溶血性曼氏杆菌A1、A2血清型标准株的灭活疫苗制备和免疫效果评价ThepreparationandImmuneefficacyevaluationoftypeA1、A2M.haemolyticavaccine研究生:胥耀文学号：2016302120049指导教师:陈建国副教授学位类型:兽医硕士领域：临床兽医学华中农业大学动物医学院中国·武汉CollegeofAnimalVeterinary,HuazhongAgriculturalUnivers

3、ityWuhan，China本研究由以下项目资助：牛羊重要细菌病新型疫苗及其工艺研究基金编号【2017YFD0500905】肉牛耗牛产业体系项目编号【CARS-37】SupportedByNewVaccineAndTechnologyResearchOnImportantBacterialDiseasesOfCattleAndSheepFundsNumber【2017YFD0500905】BeefAndYakIndustrialSystem,ProjectNumber【CARS-37】溶血性曼氏杆菌A1、A2血清型标准株的灭活疫苗制备和免疫效果分析目录摘要........

4、.........................................................................................................................1Abstract................................................................................................................................3缩略语表（Abbreviation）............

5、....................................................................................51前言..................................................................................................................................61.1研究问题的由来............................................................

6、............................................61.2文献综述....................................................................................................................61.2.1溶血性曼氏杆菌病原学特征.............................................................................61.2.2溶血性曼氏杆菌毒力因子.........

7、........................................................................71.2.3流行病学特点.....................................................................................................81.2.4国内外疫苗研究进展..................................................................