慢肾康宁在uuo大鼠肾间质纤维化wnt2fβ-catenin信号通路中的影响

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1、暨南大学2011级硕士研究生学位论文缩略词表缩略词英文全称中文全称RIFRenalinterstitialfibrosis肾间质纤维化CKDChronickidneydisease慢性肾脏病CRFChronicrenalfailure慢性肾衰竭E-cadherinE-cadherinE-钙黏蛋白UUOunilateralureteralobstruction单侧输尿管梗阻β-cateninβ-cateninβ-连环蛋白ColⅢCollagentypeⅢⅢ型胶原蛋白TGF-β1transforminggrowthfacto

2、r-β1转化生长因子β1HGFhepatocytegrowthfactor肝细胞生长因子BMP-7bonemorphogeneticprotein-7骨形成蛋白-7ESRDEndstagerenaldisease终末期肾脏病AngⅡangiotensinⅡ血管紧张素ⅡGFRGlomerularfiltrationrate肾小球率过滤ECMExtracellularMatrix细胞外基质α-SMAα-Smoothmuscleactinα-平滑肌肌动蛋白HEHematoxylinandeosinstaining苏木精和伊红染

3、色PBSphosphatebuffersolution磷酸盐缓冲液EMTepithelialmesenchymaltransition肾小管上皮细胞间充质转分化MFBmyofibroblast肌成纤维细胞DNdiabeticnephropathy糖尿病肾病IV暨南大学2011级硕士研究生学位论文目录中文摘要..................................................................IABSTRACT..................................

4、...............................II缩略词表.................................................................IV目录....................................................................V前言....................................................................1第一部分理论研究.........

5、................................................31.现代医学对肾间质纤维化的研究进展....................................32.中医对肾间质纤维化的研究...........................................12第二部分实验部分........................................................201.实验材料............................

6、...............................202.实验方法和步骤.....................................................223.实验结果...........................................................28第三部分讨论...........................................................391.肾间质纤维化的动物模型的探讨................

7、.......................392.慢肾康宁的组方依据.................................................393.慢肾康宁对UUO大鼠肾间质纤维化的保护作用..........................404.慢肾康宁对Wnt4/β-catenin通路的影响..............................405.不足与展望........................................................41结论

8、.....................................................................43参考文献.................................................................44在校期间发表的论文........