慢肾康宁对uuo大鼠肾间质纤维化中tgf-β12fsmad3信号调控的mir-21、mir-29表达的影响

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1、暨南大学2012级硕士研究生学位论文缩略词表缩略词英文全称中文全称CKDchronickidneydisease慢性肾脏病ESRDend-stagerenaldisease终末期肾脏疾病RIFrenalinterstitialfibrosis肾间质纤维化EMTepithelial-mesenchymaltransition上皮细胞向间充质转分化ECMextracellularmatrix细胞外基质GFRglomerularfiltrationrate肾小球滤过率Myo-FBmyo-fibroblast肌成纤维细胞E-cadherinE-cadherinE钙黏蛋白α-SMAα-Smooth

2、muscleactinα-平滑肌肌动蛋白VimentinVimentin波形蛋白FNfibronectin纤维连接蛋白LNlaminin层黏连蛋白PAplasminogenactivator纤溶酶原激活物CTGFconnectivetissuegrowthfactor结缔组织生长因子AngⅡAngiotensinⅡ血管紧张素ⅡBMP-7Bonemorphogeneticprotein-7骨形态发生蛋白-7TGF-β1Transforminggrowthfactor-β1转化生长因子-β1lncRNAslongnoncodingRNAs长链非编码RNAmiRNAmicroRNA微小RNAU

3、UOunilateralureteralobstruction单侧输尿管梗阻HEHematoxylinandeosinstaining苏木精和伊红染色PBSphosphatebuffersolution磷酸盐缓冲液III万方数据暨南大学2012级硕士研究生学位论文目录中文摘要.....................................................................................................................................IABSTRACT.................

4、..............................................................................................................II缩略词表..................................................................................................................................III目录..............................................

5、........................................................................................IV前言........................................................................................................................................1第一部分理论研究............................................................

6、......................................................21.现代医学对肾间质纤维化的研究进展..........................................................................22.中医对肾间质纤维化的研究..........................................................................................8第二部分实验部分....................................

7、............................................................................161.实验材料........................................................................................................................162.实验方法和步骤...