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1、Article†LongNoncodingRNAsExpressionProfileoftheDevelopingMouseHeartShortTitle:lncRNAsprofileindevelopingmouseheart*,1*,23343JinGaiZhu,YaHuiShen,HaiLangLiu,MingLiu,YaQingShen,XiangQingKong,GuiXian3,#3,#Song,LingMeiQian1DepartmentofPediatrics,NanjingMate
2、rnityandChildHealthCareHospitalAffiliatedtoNanjingMedicalUniversity,Nanjing210029,People’sRepublicofChina2DepartmentofMICU,NanjingMaternityandChildHealthCareHospitalAffiliatedtoNanjingMedicalUniversity,Nanjing210029,People’sRepublicofChina3Departmentof
3、Cardiology,TheFirstAffiliatedHospitalofNanjingMedicalUniversity,Nanjing210029,People’sRepublicofChina4DepartmentofLaboratorymedicine,TaizhouMaternityandChildHealthCareHospital,Taizhou225300,People’sRepublicofChina#Correspondingauthors:LingMeiQian,Depar
4、tmentofCardiology,TheFirstAffiliatedHospitalofNanjingMedicalUniversity,Nanjing210029,People’sRepublicofChina.E-mail:lmqian@njmu.edu.cnGuiXianSong,DepartmentofCardiology,TheFirstAffiliatedHospitalofNanjingMedicalUniversity,Nanjing210029,People’sRepublic
5、ofChina.E-mail:songguixian1983@163.com*Theseauthorscontributedequallytothiswork.ConflictofInterest:Noconflictofinterestexistsinthesubmissionofthismanuscript.KEYWORDS:Heartdevelopment,LongnoncodingRNA,Microarray,Bioinformatics†Thisarticlehasbeenaccepted
6、forpublicationandundergonefullpeerreviewbuthasnotbeenthroughthecopyediting,typesetting,paginationandproofreadingprocess,whichmayleadtodifferencesbetweenthisversionandtheVersionofRecord.Pleasecitethisarticleasdoi:[10.1002/jcb.24733]Received26September20
7、13;Revised24November2013;Accepted4December2013JournalofCellularBiochemistry©2013WileyPeriodicals,Inc.DOI10.1002/jcb.24733ABSTRACTLongnoncodingRNAs(lncRNAs)representasub-groupofnoncodingRNAsthatarelongerthan200nucleotides.ThecharacterizationoflncRNAsand
8、theiracceptanceascrucialregulatorsofnumerousdevelopmentalandbiologicalpathwayshavesuggestedthatthelncRNAstudyhasgraduallybecomeoneofthehottopicsinthefieldofRNAbiology.ManylncRNAsshowspatiallyandtemporallyrestrictedexpressionpatternsduri
