资源描述：
《Transcriptome analysis demonstrate widespread differential expression of long noncoding RNAs involve in Larimichthys crocea immune response》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、Fish&ShellfishImmunology51(2016)1e8ContentslistsavailableatScienceDirectFish&ShellfishImmunologyjournalhomepage:www.elsevier.com/locate/fsiFulllengtharticleTranscriptomeanalysisdemonstratewidespreaddifferentialexpressionoflongnoncodingRNAsinvolveinLarimichthyscroce
2、aimmuneresponseaaaaba,*LihuaJiang,WeiLiu,AiyiZhu,JiansheZhang,JiajianZhou,ChangwenWuaNationalEngineeringResearchCenterofMariculturalFacilitiesofChina,CollegeofMarineScienceandTechnology,ZhejiangOceanUniversity,Zhoushan,ChinabBsgenomicsCo.,Ltd.,Shenzhen,Chinaartic
3、leinfoabstractArticlehistory:LongnoncodingRNAs(lncRNAs)areaclassoftranscriptsthatlongerthan200bpanddonotencodeReceived19October2015proteins.Recentgenome-widestudiesofvertebratetranscriptomeshaveannotatedlncRNAsthatareReceivedinrevisedformexpressedinvarioustissues
4、anddevelopmentstages.Thedraftgenomeandseveraltranscriptome19January2016sequencingdatasetshavebeencollectedforthestudyofprotein-codinggenesinlargeyellowcroakerAccepted3February2016(Larimichthyscrocea),butlittleisknownabouttheexpressionandfunctionalrolesoflncRNAsin
5、thisAvailableonline15February2016species.InordertoobtainacatalogoflncRNAsforlargeyellowcroaker,severalRNA-seqdatasetswereintegratedfromvarioustissuesincludingegg,muscle,liver,andspleen.Atotalof48,953high-confidenceKeywords:transcriptswerereconstructedin38,017loci,
6、recoveringthemostofexpressedreferencetranscriptsRNA-seqLongnoncodingRNAswhilethousandsofnovelexpressedlocihavebeenidentified.ThetissueexpressionprofilerevealedthatImmuneresponsemostlncRNAswerespecificallyenrichedindifferenttissues.Astringentsetof210lncRNAswereiden-L
7、arimichthyscroceatifiedasbeingspecificallyexpressedinspleenandpotentiallyinvolvedinimmuneresponse.OurstudyfirstsystematicallyidentifylncRNAsinlargeyellowcroaker,benefitingthefuturegenomicstudyofthisspecies.©2016ElsevierLtd.Allrightsreserved.1.IntroductionmRNA,butshow
8、lesssequenceconservationacrossmultiplespe-cies[6].AmongthereportedlncRNAs,H19andXistweresomeofThedevelopmentofhighthroughputsequencingtechnologytheearliestones
