右美托咪定对高血压病人甲状腺手术中血流动力学的影响

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1、右美托咪定对高血压患者甲状腺手术中血流动力学的影响摘要目的：观察右美托咪定对高血压患者甲状腺手术中血流动力学的影响。方法：将60例行甲状腺手术的高血压患者随机分为右美托咪定组(D组)和安慰剂组(C组)，每组30例。D组于麻醉前10分钟泵注右美托咪定0．699／kg，后以0．499／kg／h速度维持给药，手术结束前5min停药，C组给予等容量生理盐水，观察T。(麻醉前)、T．(手术开始后5min)、T。(剥离甲状腺上下级时)、T。(手术结束时)患者的HR、MAP及术毕病人恢复情况(苏醒时间、拔管时间)及拔管时Ramsay评分。结果：C组Tl，T：，T。，T。

2、时间点MAP、HR值与T。比较有明显差异(P

3、tofdexmedetomidineinhypertensivepatientsundergoingsurgeryforthyroidglandunderGeneralAnesthesiaAbstractObjective：ToinvestigatethepreventiveeffectofintravenousinjectionofDexmedetomidineinhypertensivepatientsundergoingsurgeryforthyroidglandunderGeneralAnesthesia．Methods：60hypertensiv

4、epatientswiththyroidglandcancerwererandomlydividedintotwogroups(Dexmedetomidine，i．e．groupDandgroupcontrol，j．e．groupC)Patientsinbothgroupsreceivedbyintravenousinjectionundergeneralanesthesia．Tenminutesbeforethebeginningofopermion，patientsinDEXgroupweregiven0．6pg／kg(finishedin10minu

5、tes)throughaminipump，andthencontinutingattherateofO．4pg，l(g／lluntiltheendoftheprocedure．PatientsinthecontrolgroupwereofferednormalslineasthesamewayforDEXgroup．Thetimeofpatientarrivedoperatingroom(To)，fiveminutesafterthebeginningofoperation(T0，immediatelyafterthestripingofthyreoide

6、asuperiorandthyreoideainferior(T2)，immediatelyoftheendofoperation(T3)，theheartrate(HR)，meanarterialpressure(MAP)，palinesthesiaTime，extubationTimeandramsayscorewererecorded．Results：Comparedwiththosepatientsincontrolgroup，theHRandMAPofpatientsinDEXgroupweresteady,andthatatTl，Tz，T3we

7、relower(P

8、diovasculareffectsandraisethesafe