移民城市成人麻疹血清流行病学特征研究

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1、移民城市成人麻疹血清流行病学特征研究王琳江鹏飞何林(深圳市龙华卫牛监督所广东深圳518109)【中图分类号1R181.3+6C文献标识码】A【文章编号】1672-5085(2012)20-0094-03【摘要】目的研究深圳成人麻疹免疫现状及其流行特征，探讨中国在城市化和工业现代化过程中人群的迁移对麻疹消除的影响。方法采用横断面流行病学研究方法；血清样木用ELISA检测麻疹IgG抗体。结果1081名成人，麻疹IgG抗体阳性775人，阳性率为71.69%,抗体阴性率高达28.31%。产妇中麻疹抗体阳性率为64.39

2、%,显著低于门诊体检人群和富士康新、老员工人群(分别为74.27%、75.42%和71.86%)；成人时期接种麻疹疫苗(以下简称“麻苗”)者麻疹抗体阳性率(78.50%)明显高于儿童时期接种麻苗(67.42%)和接种史不详者(73.39%)；而产妇中成人时期麻苗接种率(2.93%)也显著低于门诊体检人群和富士康新、老员工人群(分别为15,53%.10.42%和10.23%)。受教育程度木科及以上者有着最低的麻疹抗体阳性率(59.15%)o结论深圳成人中存在着高比例的麻疹易感人群；开展成人，尤其是年轻育龄妇女等重

3、点人群麻苗强化免疫是实现移民城市麻疹消除目标的关键措施。【关键词】移民成人麻疹抗体血清流行病学；AStudyofSeroepidemiologyforMeaslesamongAdultinImmigration【Abstract]ObjectiveToknowabouttheimmunelevelandepidemiologicalcharacteristicofmeaslesamongadultatShenzhenCityandtodiscussedinflueneeoftheeliminationforme

4、aslesintheprocesstomigratepopulationforurbanizationandindustrialmodernizationinChina.MethodsAcross-sectionalepidemiologicalinvestigationwasapplied.TheserumsampleswereexaminedwithenzymeimmuneassaysformeaslesspecificIgGantibody.ResultsAtotalof1081adultwereinve

5、stigated.TherateofpositiveandrateofnegativeformeaslesspecificIgGantibodywere71.69%and28.31%,respectively.TherateofpositiveformeaslesspecificIgGantibodyamongmaternal(64.39%)weresignificantlylowerthanhealthypeopleofmedicalexaminationatoutpatient,newemployeesat

6、FoxconnandolderemployeesatFoxconn(74.27%、75.42%和71.86%,respectively).TherateofpositiveformeaslesspecificIgGantibodyamonggroupsduringtheadultinoculatedvaccineofmeasles(78.50%)weresigrdficantlyhigherthangroupsduringchildreninoculatedvaccineofmeasles(67.42%)and

7、groupsforhistoryofvaccinationunknown(73.39%).Therateofvaccinationduringtheadultinoculatedvaccineofmeaslesamongmaternal(2.93%)wassignificantlylowerthanhealthypeopleofmedicalexaminationatoutpatient,newemployeesatFoxconnandolderemployeesatFoxconn(15.53%、10.42%a

8、nd10.23%,respectively).Theadultforbachelordegreeorabovelevelofeducationhasthelowestrateofpositiveforantibodyofmeasles(59.15%).ConclusionAmongadulthassusceptiblepopulationofhighproportiontomeasle